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Article

Positron Emission Intensity in the Decay of 86gY for Use in Dosimetry Studies

1
Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich, D-52425 Jülich, Germany
2
Tandem Accelerator Facilities, INST, Atomic Energy Research Establishment, Savar, Dhaka 1000, Bangladesh
3
Nuclear Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
4
Department of Nuclear Engineering, UC Berkeley, Berkeley, CA 94720, USA
*
Author to whom correspondence should be addressed.
Academic Editors: Kazuma Ogawa, Shigeki Watanabe and Ryuichi Nishii
Molecules 2022, 27(3), 768; https://doi.org/10.3390/molecules27030768
Received: 22 November 2021 / Revised: 11 January 2022 / Accepted: 17 January 2022 / Published: 25 January 2022
(This article belongs to the Special Issue Recent Advances in Techniques with Radionuclide for Theranostic Drugs)
The β+-emitting radionuclide 86gY (t1/2 = 14.7 h) forms a matched-pair with the β-emitting therapeutic radionuclide 90Y (t1/2 = 2.7 d) for theranostic application in medicine. This approach demands a precise knowledge of the positron emission probability of the PET nuclide which was until recently rather uncertain for 86gY. In this work, an 86gY source of high radionuclidic purity was prepared and a direct measurement of the positron emission intensity per 100 decay of the parent (hereafter “positron emission intensity”) was performed using high-resolution HPGe detector γ-ray spectroscopy. The electron capture intensity was also determined as an additional check by measuring the Kα and Kβ X-rays of energies 14.1 and 15.8 keV, respectively, using a low energy HPGe detector. From those measurements, normalized values of 27.2 ± 2.0% for β+-emission and 72.8 ± 2.0% for EC were obtained. These results are in excellent agreement with values recently reported in the literature based on a detailed decay scheme study. View Full-Text
Keywords: positron emission; electron capture; gamma-ray; X-ray; 86gY radionuclide; matched-pair; theranostic application positron emission; electron capture; gamma-ray; X-ray; 86gY radionuclide; matched-pair; theranostic application
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MDPI and ACS Style

Uddin, M.S.; Qaim, S.M.; Scholten, B.; Basunia, M.S.; Bernstein, L.A.; Spahn, I.; Neumaier, B. Positron Emission Intensity in the Decay of 86gY for Use in Dosimetry Studies. Molecules 2022, 27, 768. https://doi.org/10.3390/molecules27030768

AMA Style

Uddin MS, Qaim SM, Scholten B, Basunia MS, Bernstein LA, Spahn I, Neumaier B. Positron Emission Intensity in the Decay of 86gY for Use in Dosimetry Studies. Molecules. 2022; 27(3):768. https://doi.org/10.3390/molecules27030768

Chicago/Turabian Style

Uddin, M. S., Syed M. Qaim, Bernhard Scholten, M. S. Basunia, Lee A. Bernstein, Ingo Spahn, and Bernd Neumaier. 2022. "Positron Emission Intensity in the Decay of 86gY for Use in Dosimetry Studies" Molecules 27, no. 3: 768. https://doi.org/10.3390/molecules27030768

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