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Strategies for Enhancing Polyester-Based Materials for Bone Fixation Applications

1
School of Engineering, Newcastle University, Newcastle upon Tyne NE1 7RU, UK
2
School of Dental Sciences, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, UK
*
Author to whom correspondence should be addressed.
Academic Editor: Marek Brzeziński
Molecules 2021, 26(4), 992; https://doi.org/10.3390/molecules26040992
Received: 21 December 2020 / Revised: 9 February 2021 / Accepted: 9 February 2021 / Published: 13 February 2021
(This article belongs to the Special Issue Polylactide-Based Materials: Synthesis and Biomedical Applications)
Polyester-based materials are established options, regarding the manufacturing of bone fixation devices and devices in routine clinical use. This paper reviews the approaches researchers have taken to develop these materials to improve their mechanical and biological performances. Polymer blending, copolymerisation, and the use of particulates and fibre bioceramic materials to make composite materials and surface modifications have all been studied. Polymer blending, copolymerisation, and particulate composite approaches have been adopted commercially, with the primary focus on influencing the in vivo degradation rate. There are emerging opportunities in novel polymer blends and nanoscale particulate systems, to tune bulk properties, and, in terms of surface functionalisation, to optimise the initial interaction of devices with the implanted environment, offering the potential to improve the clinical performances of fracture fixation devices. View Full-Text
Keywords: biomaterials; polyesters; polymer blends; copolymers; biodegradable materials; bone regeneration; mechanical properties; composites; glass fibres biomaterials; polyesters; polymer blends; copolymers; biodegradable materials; bone regeneration; mechanical properties; composites; glass fibres
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MDPI and ACS Style

Naseem, R.; Tzivelekis, C.; German, M.J.; Gentile, P.; Ferreira, A.M.; Dalgarno, K. Strategies for Enhancing Polyester-Based Materials for Bone Fixation Applications. Molecules 2021, 26, 992. https://doi.org/10.3390/molecules26040992

AMA Style

Naseem R, Tzivelekis C, German MJ, Gentile P, Ferreira AM, Dalgarno K. Strategies for Enhancing Polyester-Based Materials for Bone Fixation Applications. Molecules. 2021; 26(4):992. https://doi.org/10.3390/molecules26040992

Chicago/Turabian Style

Naseem, Raasti, Charalampos Tzivelekis, Matthew J. German, Piergiorgio Gentile, Ana M. Ferreira, and Kenny Dalgarno. 2021. "Strategies for Enhancing Polyester-Based Materials for Bone Fixation Applications" Molecules 26, no. 4: 992. https://doi.org/10.3390/molecules26040992

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