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Review

Recent Advances in Micro/Nanomaterial-Based Aptamer Selection Strategies

1
Center for Applied Life Science, Hanbat National University, Daejeon 34158, Korea
2
School of Integrative Engineering, Chung-Ang University, Seoul 06974, Korea
*
Authors to whom correspondence should be addressed.
Academic Editors: Emilia Iglesias Martínez and Carlos Bravo Díaz
Molecules 2021, 26(17), 5187; https://doi.org/10.3390/molecules26175187
Received: 3 August 2021 / Revised: 20 August 2021 / Accepted: 24 August 2021 / Published: 26 August 2021
Aptamers are artificial nucleic acid ligands that have been employed in various fundamental studies and applications, such as biological analyses, disease diagnostics, targeted therapeutics, and environmental pollutant detection. This review focuses on the recent advances in aptamer discovery strategies that have been used to detect various chemicals and biomolecules. Recent examples of the strategies discussed here are based on the classification of these micro/nanomaterial-mediated systematic evolution of ligands by exponential enrichment (SELEX) platforms into three categories: bead-mediated, carbon-based nanomaterial-mediated, and other nanoparticle-mediated strategies. In addition to describing the advantages and limitations of the aforementioned strategies, this review discusses potential strategies to develop high-performance aptamers. View Full-Text
Keywords: aptamer; SELEX; biomolecule; screening; affinity; specificity; library aptamer; SELEX; biomolecule; screening; affinity; specificity; library
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MDPI and ACS Style

Kim, D.-M.; Go, M.-J.; Lee, J.; Na, D.; Yoo, S.-M. Recent Advances in Micro/Nanomaterial-Based Aptamer Selection Strategies. Molecules 2021, 26, 5187. https://doi.org/10.3390/molecules26175187

AMA Style

Kim D-M, Go M-J, Lee J, Na D, Yoo S-M. Recent Advances in Micro/Nanomaterial-Based Aptamer Selection Strategies. Molecules. 2021; 26(17):5187. https://doi.org/10.3390/molecules26175187

Chicago/Turabian Style

Kim, Dong-Min, Myeong-June Go, Jingyu Lee, Dokyun Na, and Seung-Min Yoo. 2021. "Recent Advances in Micro/Nanomaterial-Based Aptamer Selection Strategies" Molecules 26, no. 17: 5187. https://doi.org/10.3390/molecules26175187

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