Next Article in Journal
Activity Guided Isolation of Phenolic Compositions from Anneslea fragrans Wall. and Their Cytoprotective Effect against Hydrogen Peroxide Induced Oxidative Stress in HepG2 Cells
Previous Article in Journal
Effective Tumor Targeting by EphA2-Agonist-Biotin-Streptavidin Conjugates
Previous Article in Special Issue
Recent Trends in Enzyme Immobilization—Concepts for Expanding the Biocatalysis Toolbox
Article

Synthesis of Chitosan-La2O3 Nanocomposite and Its Utility as a Powerful Catalyst in the Synthesis of Pyridines and Pyrazoles

1
Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt
2
Department of Chemistry, Faculty of Science, Taibah University, Al-Madinah Almunawarah, Yanbu 46423, Saudi Arabia
3
Department of Chemistry, College of Science, Taibah University, Al-Madinah Almunawrah 30002, Saudi Arabia
4
Biological and Environmental Sciences & Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia
5
Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah Almukaramah 21514, Saudi Arabia
6
Chemistry Department, Faculty of Science, Alexandria University, Alexandria 21321, Egypt
*
Author to whom correspondence should be addressed.
Academic Editor: Alessandra Puglisi
Molecules 2021, 26(12), 3689; https://doi.org/10.3390/molecules26123689
Received: 21 May 2021 / Revised: 7 June 2021 / Accepted: 8 June 2021 / Published: 17 June 2021
(This article belongs to the Special Issue The Latest Trends in Catalyst Immobilization)
Recently, the development of nanocatalysts based on naturally occurring polysaccharides has received a lot of attention. Chitosan (CS), as a biodegradable and biocompatible polysaccharide, is considered to be an excellent template for the design of a hybrid biopolymer-based metal oxide nanocomposite. In this case, lanthanum oxide nanoparticles doped with chitosan at different weight percentages (5, 10, 15, and 20 wt% CS/La2O3) were prepared via a simple solution casting method. The prepared CS/La2O3 nanocomposite solutions were cast in a Petri dish in order to produce the developed catalyst, which was shaped as a thin film. The structural features of the hybrid nanocomposite film were studied by FTIR, SEM, and XRD analytical tools. FTIR spectra confirmed the presence of the major characteristic peaks of chitosan, which were modified by interaction with La2O3 nanoparticles. Additionally, SEM graphs showed dramatic morphological changes on the surface of chitosan, which is attributed to surface adsorption with La2O3 molecules. The prepared CS/La2O3 nanocomposite film (15% by weight) was investigated as an effective, recyclable, and heterogeneous base catalyst in the synthesis of pyridines and pyrazoles. The nanocomposite used was sufficiently stable and was collected and reused more than three times without loss of catalytic activity. View Full-Text
Keywords: chitosan; La2O3; nanocomposite film; heterogeneous catalysis; pyridines; pyrazoles chitosan; La2O3; nanocomposite film; heterogeneous catalysis; pyridines; pyrazoles
Show Figures

Graphical abstract

MDPI and ACS Style

Khalil, K.D.; Riyadh, S.M.; Jaremko, M.; Farghaly, T.A.; Hagar, M. Synthesis of Chitosan-La2O3 Nanocomposite and Its Utility as a Powerful Catalyst in the Synthesis of Pyridines and Pyrazoles. Molecules 2021, 26, 3689. https://doi.org/10.3390/molecules26123689

AMA Style

Khalil KD, Riyadh SM, Jaremko M, Farghaly TA, Hagar M. Synthesis of Chitosan-La2O3 Nanocomposite and Its Utility as a Powerful Catalyst in the Synthesis of Pyridines and Pyrazoles. Molecules. 2021; 26(12):3689. https://doi.org/10.3390/molecules26123689

Chicago/Turabian Style

Khalil, Khaled D., Sayed M. Riyadh, Mariusz Jaremko, Thoraya A. Farghaly, and Mohamed Hagar. 2021. "Synthesis of Chitosan-La2O3 Nanocomposite and Its Utility as a Powerful Catalyst in the Synthesis of Pyridines and Pyrazoles" Molecules 26, no. 12: 3689. https://doi.org/10.3390/molecules26123689

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop