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Review
Peer-Review Record

Recent Advances in Studying Interfacial Adsorption of Bioengineered Monoclonal Antibodies

Molecules 2020, 25(9), 2047; https://doi.org/10.3390/molecules25092047
by Peter Hollowell 1, Zongyi Li 1, Xuzhi Hu 1, Sean Ruane 1, Cavan Kalonia 2, Christopher F. van der Walle 3,† and Jian R. Lu 1,*
Reviewer 1:
Reviewer 2: Anonymous
Molecules 2020, 25(9), 2047; https://doi.org/10.3390/molecules25092047
Submission received: 5 February 2020 / Revised: 13 March 2020 / Accepted: 23 April 2020 / Published: 28 April 2020

Round 1

Reviewer 1 Report

The work "Recent Advances in Studying Interfacial Adsorption of Bioengineered Monoclonal Antibodies" is concern to show how some techniques used in material science can be useful to study a biological system. The review made to Monoclonal antibodies (mAbs) was appropriate to understand the techniques in this context. A special attention was dedicated to mAbs at interfaces which is recognized in this work, mainly about valuable information on recent experiments.

Author Response

Thank you very much for your positive comments

Reviewer 2 Report

Timely article and broad groud covered. 

Consider revising title and adding more information around pre-formulation strategies... and such pref-formulation focus brought into the title will attract readers involved in this area.

Author Response

I think changing the title would be a large leap but further information about biopharmaceutical production has been added and streamlined to help highlight more specifically where the issues with protein adsorption lie.

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