Biodegradable Cell Microcarriers Based on Chitosan/Polyester Graft-Copolymers
Abstract
:1. Introduction
2. Results and Discussion
2.1. Microsphere Formation, Size Distribution and Recovery Yield
2.2. In Vitro Analysis of the Biocompatibility of the Microparticles
3. Materials and Methods
3.1. Copolymer’s Synthesis and Characterization
3.2. Preparation and Characterization of the Microspheres
3.3. Cell Cultivation on the Microparticles
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Sample Availability: Samples of the compounds are available from the authors. |
Sample Code | Component Content, wt.% | Temperature, °C | |||
---|---|---|---|---|---|
chitosan | poly(L-lactide) | PLGA | gelatin | ||
CPLG | 60 | − | 40 | − | 60 |
CPG | 35 | 52 | − | 13 | 100 |
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Demina, T.S.; Drozdova, M.G.; Sevrin, C.; Compère, P.; Akopova, T.A.; Markvicheva, E.; Grandfils, C. Biodegradable Cell Microcarriers Based on Chitosan/Polyester Graft-Copolymers. Molecules 2020, 25, 1949. https://doi.org/10.3390/molecules25081949
Demina TS, Drozdova MG, Sevrin C, Compère P, Akopova TA, Markvicheva E, Grandfils C. Biodegradable Cell Microcarriers Based on Chitosan/Polyester Graft-Copolymers. Molecules. 2020; 25(8):1949. https://doi.org/10.3390/molecules25081949
Chicago/Turabian StyleDemina, Tatiana S., Maria G. Drozdova, Chantal Sevrin, Philippe Compère, Tatiana A. Akopova, Elena Markvicheva, and Christian Grandfils. 2020. "Biodegradable Cell Microcarriers Based on Chitosan/Polyester Graft-Copolymers" Molecules 25, no. 8: 1949. https://doi.org/10.3390/molecules25081949