Next Article in Journal
Effects of Orange Extracts on Longevity, Healthspan, and Stress Resistance in Caenorhabditis elegans
Previous Article in Journal
Methods of the Analysis of Oxylipins in Biological Samples
Previous Article in Special Issue
Phyto-Nanocatalysts: Green Synthesis, Characterization, and Applications
Open AccessArticle

Efficient and Stable Magnetic Chitosan-Lipase B from Candida Antarctica Bioconjugates in the Enzymatic Kinetic Resolution of Racemic Heteroarylethanols

Biocatalysis and Biotransformation Research Center, Babeș-Bolyai University, Arany János 11, Cluj-Napoca 400028, Romania
*
Author to whom correspondence should be addressed.
Academic Editors: Simona M. Coman; Madalina Tudorache, Simona M. Coman and Madalina Tudorache
Molecules 2020, 25(2), 350; https://doi.org/10.3390/molecules25020350
Received: 17 December 2019 / Revised: 9 January 2020 / Accepted: 13 January 2020 / Published: 15 January 2020
(This article belongs to the Special Issue New Approaches in Green Catalysis)
Lipase B from Candida antarctica immobilized by covalent binding on sebacoyl-activated chitosan-coated magnetic nanoparticles proved to be an efficient biocatalyst (49.2–50% conversion in 3–16 h and >96% enantiomeric excess) for the enzymatic kinetic resolution of some racemic heteroarylethanols through transesterification with vinyl acetate. Under optimal conditions (vinyl acetate, n-hexane, 45 °C), the biocatalyst remains active after 10 cycles. View Full-Text
Keywords: lipase B from Candida antarctica; magnetic nanoparticle; chitosan; covalent immobilization; enzymatic kinetic resolution lipase B from Candida antarctica; magnetic nanoparticle; chitosan; covalent immobilization; enzymatic kinetic resolution
Show Figures

Graphical abstract

MDPI and ACS Style

Spelmezan, C.G.; Bencze, L.C.; Katona, G.; Irimie, F.D.; Paizs, C.; Toșa, M.I. Efficient and Stable Magnetic Chitosan-Lipase B from Candida Antarctica Bioconjugates in the Enzymatic Kinetic Resolution of Racemic Heteroarylethanols. Molecules 2020, 25, 350.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop