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Molecules 2019, 24(3), 591;

Development and Optimization of the Biological Conversion of Ethane to Ethanol Using Whole-Cell Methanotrophs Possessing Methane Monooxygenase

Department of Chemical Engineering, Kyung Hee University, Gyeonggi-do 17104, Korea
Department of Chemical Engineering, Changwon University, Changwon 51140, Korea
Author to whom correspondence should be addressed.
Academic Editors: Rafael Luque and Luís Adriano Santos Do Nascimento
Received: 24 January 2019 / Revised: 4 February 2019 / Accepted: 5 February 2019 / Published: 7 February 2019
(This article belongs to the Special Issue Advances in Conversion of Biomass and Waste to Chemicals and Fuels)
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The biological production of ethanol from ethane for the utilization of ethane in natural gas was investigated under ambient conditions using whole-cell methanotrophs possessing methane monooxygenase. Several independent variables including ethane concentration and biocatalyst amounts, among other factors, were optimized for the enhancement of ethane-to-ethanol bioconversion. We obtained 0.4 g/L/h of volumetric productivity and 0.52 g/L of maximum titer in optimum batch reaction conditions. In this study, we demonstrate that the biological gas-to-liquid conversion of ethane to ethanol has potent technical feasibility as a new application of ethane gas. View Full-Text
Keywords: methane monooxygenase; methanotrophs; ethane; ethanol; gas-to-liquid methane monooxygenase; methanotrophs; ethane; ethanol; gas-to-liquid

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Oh, S.H.; Hwang, I.Y.; Lee, O.K.; Won, W.; Lee, E.Y. Development and Optimization of the Biological Conversion of Ethane to Ethanol Using Whole-Cell Methanotrophs Possessing Methane Monooxygenase. Molecules 2019, 24, 591.

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