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Article

Flowers of Astragalus membranaceus var. mongholicus as a Novel High Potential By-Product: Phytochemical Characterization and Antioxidant Activity

1
Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, State Administration of Traditional Chinese Medicine Key Laboratory of Chinese Medicinal Resources Recycling Utilization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China
2
School of Pharmacy, Ningxia Medical University, Yinchuan 750021, China
*
Authors to whom correspondence should be addressed.
Molecules 2019, 24(3), 434; https://doi.org/10.3390/molecules24030434
Submission received: 6 January 2019 / Revised: 22 January 2019 / Accepted: 22 January 2019 / Published: 25 January 2019
(This article belongs to the Special Issue The Antioxidant Capacities of Natural Products 2019)

Abstract

The root of Astragalus membranaceus var. mongholicus is one of the most popular herbal medicines worldwide. In order to increase the yield of underground roots of A. membranaceus var. mongholicus, its flowers (AMF) have often been removed in their flowering stage, which produces the flowers as waste being discarded. To explore its phytochemicals and potential value for utilization, the antioxidant activities of extracts from AMF were evaluated by a free radical scavenging assay and reducing power assay. The total phenols and flavonoids, as well as the individual compounds, in different extracts of AMF were also investigated. The results showed that the extract ME obtained from AMF through macroporous resins separation exhibited strong antioxidant activities, which were close to those of positive control BHT. ME was rich in phenolic acids and flavonoids, and the contents reached 108.42 mg gallic acid equivalents/g and 265.70 mg rutin equivalents/g, respectively. A total of 31 compounds, including four phenolic acids, nineteen flavonoids, three isoflavones, two pterocarpans, and three saponins, were identified using UPLC-QTOF-MS in ME. Quantitative analysis of sixteen components in the extracts of AMF showed that flavonoids were the predominant constituents, especially for the compounds of hyperoside, rutin, and isorhamnetin-3-O-β-d-glucoside.
Keywords: Astragalus membranaceus var. mongholicus; antioxidant activity; flavonoid; phenolic acid Astragalus membranaceus var. mongholicus; antioxidant activity; flavonoid; phenolic acid

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MDPI and ACS Style

Li, Y.; Guo, S.; Zhu, Y.; Yan, H.; Qian, D.-w.; Wang, H.-q.; Yu, J.-q.; Duan, J.-a. Flowers of Astragalus membranaceus var. mongholicus as a Novel High Potential By-Product: Phytochemical Characterization and Antioxidant Activity. Molecules 2019, 24, 434. https://doi.org/10.3390/molecules24030434

AMA Style

Li Y, Guo S, Zhu Y, Yan H, Qian D-w, Wang H-q, Yu J-q, Duan J-a. Flowers of Astragalus membranaceus var. mongholicus as a Novel High Potential By-Product: Phytochemical Characterization and Antioxidant Activity. Molecules. 2019; 24(3):434. https://doi.org/10.3390/molecules24030434

Chicago/Turabian Style

Li, Yuan, Sheng Guo, Yue Zhu, Hui Yan, Da-wei Qian, Han-qing Wang, Jian-qiang Yu, and Jin-ao Duan. 2019. "Flowers of Astragalus membranaceus var. mongholicus as a Novel High Potential By-Product: Phytochemical Characterization and Antioxidant Activity" Molecules 24, no. 3: 434. https://doi.org/10.3390/molecules24030434

APA Style

Li, Y., Guo, S., Zhu, Y., Yan, H., Qian, D.-w., Wang, H.-q., Yu, J.-q., & Duan, J.-a. (2019). Flowers of Astragalus membranaceus var. mongholicus as a Novel High Potential By-Product: Phytochemical Characterization and Antioxidant Activity. Molecules, 24(3), 434. https://doi.org/10.3390/molecules24030434

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