Next Article in Journal
Similar Safety Profile of the Enantiomeric N-Aminoalkyl Derivatives of Trans-2-Aminocyclohexan-1-ol Demonstrating Anticonvulsant Activity
Previous Article in Journal
A Promising Polymer Blend Electrolytes Based on Chitosan: Methyl Cellulose for EDLC Application with High Specific Capacitance and Energy Density
Article Menu
Issue 13 (July-1) cover image

Export Article

Open AccessArticle

Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’

1
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-Cho, Tokushima 770-8514, Japan
2
Kawano-Mericlone Co. Ltd., Wakimachi, Tokushima 779-3604, Japan
3
Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan
4
Faculty of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan
5
School of pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan
*
Author to whom correspondence should be addressed.
Molecules 2019, 24(13), 2504; https://doi.org/10.3390/molecules24132504
Received: 2 July 2019 / Revised: 5 July 2019 / Accepted: 6 July 2019 / Published: 9 July 2019
(This article belongs to the Section Natural Products Chemistry)
  |  
PDF [2804 KB, uploaded 9 July 2019]
  |     |  

Abstract

Seven novel norcycloartane glycosides, maryloside A–G (17), were isolated from the leaves of Cymbidium Great Flower ‘Marylaurencin’, along with a known norcycloartane glycoside, cymbidoside (8). These structures were determined on the basis of mainly NMR experiments as well as chemical degradation and X-ray crystallographic analysis. The isolated compounds (16 and 8) were evaluated for the inhibitory activity on lipopolysaccharide (LPS) and interferon-γ (IFN-γ)-stimulated nitric oxide (NO) production in RAW 264.7 cells. Consequently, 1 and 3 exhibited moderate activity. View Full-Text
Keywords: Cymbidium Great Flower ‘Marylaurencin’; Orchidaceae; maryloside; nitric oxide production; norcycloartane glycoside Cymbidium Great Flower ‘Marylaurencin’; Orchidaceae; maryloside; nitric oxide production; norcycloartane glycoside
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Yoneyama, T.; Iseki, K.; Noji, M.; Imagawa, H.; Hashimoto, T.; Kawano, S.; Baba, M.; Kashiwada, Y.; Yahagi, T.; Matsuzaki, K.; Umeyama, A. Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower ‘Marylaurencin’. Molecules 2019, 24, 2504.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top