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Open AccessFeature PaperReview

Chemical Synthesis of Rare, Deoxy-Amino Sugars Containing Bacterial Glycoconjugates as Potential Vaccine Candidates

Department of Chemistry, Indian Institute of Technology Bombay, Mumbai 400076, India
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Author to whom correspondence should be addressed.
Molecules 2018, 23(8), 1997; https://doi.org/10.3390/molecules23081997
Received: 10 July 2018 / Revised: 4 August 2018 / Accepted: 8 August 2018 / Published: 10 August 2018
(This article belongs to the Special Issue Conjugate Vaccines from Carbohydrate Antigens)
Bacteria often contain rare deoxy amino sugars which are absent in the host cells. This structural difference can be harnessed for the development of vaccines. Over the last fifteen years, remarkable progress has been made toward the development of novel and efficient protocols for obtaining the rare sugar building blocks and their stereoselective assembly to construct conjugation ready bacterial glycans. In this review, we discuss the total synthesis of a variety of rare sugar containing bacterial glycoconjugates which are potential vaccine candidates. View Full-Text
Keywords: bacterial glycoconjugates; rare deoxy-amino sugars; total synthesis; vaccine candidates; zwitterionic polysaccharides; stereoselective glycosylation bacterial glycoconjugates; rare deoxy-amino sugars; total synthesis; vaccine candidates; zwitterionic polysaccharides; stereoselective glycosylation
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MDPI and ACS Style

Behera, A.; Kulkarni, S.S. Chemical Synthesis of Rare, Deoxy-Amino Sugars Containing Bacterial Glycoconjugates as Potential Vaccine Candidates. Molecules 2018, 23, 1997. https://doi.org/10.3390/molecules23081997

AMA Style

Behera A, Kulkarni SS. Chemical Synthesis of Rare, Deoxy-Amino Sugars Containing Bacterial Glycoconjugates as Potential Vaccine Candidates. Molecules. 2018; 23(8):1997. https://doi.org/10.3390/molecules23081997

Chicago/Turabian Style

Behera, Archanamayee; Kulkarni, Suvarn S. 2018. "Chemical Synthesis of Rare, Deoxy-Amino Sugars Containing Bacterial Glycoconjugates as Potential Vaccine Candidates" Molecules 23, no. 8: 1997. https://doi.org/10.3390/molecules23081997

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