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Molecules 2018, 23(7), 1539; https://doi.org/10.3390/molecules23071539

Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata

1
School of Pharmacy, Zunyi Medical University, Zunyi 563006, China
2
School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
*
Author to whom correspondence should be addressed.
Received: 17 May 2018 / Revised: 14 June 2018 / Accepted: 22 June 2018 / Published: 26 June 2018
(This article belongs to the Special Issue Advances in Plant Alkaloid Research)
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Abstract

A novel isoquinoline alkaloid, mahimbrine A, possessing a rare benzotropolone framing scaffold, was isolated from the endemic plant of Mahonia imbricata. Its structure was established on the basis of extensive spectroscopic analysis. A plausible biosynthetic route of mahimbrine A was proposed. Mahimbrine A showed no antimicrobial activity at the concentration of 1 mg/mL. View Full-Text
Keywords: Mahonia imbricata; Berberidaceae; isoquinoline alkaloid; mahimbrine A Mahonia imbricata; Berberidaceae; isoquinoline alkaloid; mahimbrine A
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Zhang, M.-S.; Deng, Y.; Fu, S.-B.; Guo, D.-L.; Xiao, S.-J. Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata. Molecules 2018, 23, 1539.

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