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Molecules 2018, 23(7), 1539;

Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata

School of Pharmacy, Zunyi Medical University, Zunyi 563006, China
School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
Author to whom correspondence should be addressed.
Received: 17 May 2018 / Revised: 14 June 2018 / Accepted: 22 June 2018 / Published: 26 June 2018
(This article belongs to the Special Issue Advances in Plant Alkaloid Research)
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A novel isoquinoline alkaloid, mahimbrine A, possessing a rare benzotropolone framing scaffold, was isolated from the endemic plant of Mahonia imbricata. Its structure was established on the basis of extensive spectroscopic analysis. A plausible biosynthetic route of mahimbrine A was proposed. Mahimbrine A showed no antimicrobial activity at the concentration of 1 mg/mL. View Full-Text
Keywords: Mahonia imbricata; Berberidaceae; isoquinoline alkaloid; mahimbrine A Mahonia imbricata; Berberidaceae; isoquinoline alkaloid; mahimbrine A

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Zhang, M.-S.; Deng, Y.; Fu, S.-B.; Guo, D.-L.; Xiao, S.-J. Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata. Molecules 2018, 23, 1539.

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