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Open AccessArticle

Detection and Identification of Estrogen Based on Surface-Enhanced Resonance Raman Scattering (SERRS)

College of Physics, Jilin Normal University, Siping 136000, China
Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education, Jilin Normal University, Changchun 130103, China
School of Electronic and Information Engineering, South China University of Technology, Guangzhou 510640, China
Department of Chemistry, Institute for Molecular Science and Fusion Technology, Kangwon National University, Chunchon 24341, Korea
Authors to whom correspondence should be addressed.
Molecules 2018, 23(6), 1330;
Received: 25 April 2018 / Revised: 28 May 2018 / Accepted: 31 May 2018 / Published: 1 June 2018
(This article belongs to the Special Issue Metal Complexes of Biological Ligands)
Many studies have shown that it is important to consider the harmful effects of phenolic hormones on the human body. Traditional UV detection has many limitations, so there is a need to develop new detection methods. We demonstrated a simple and rapid surface-enhanced resonance Raman scattering (SERRS) based detection method of trace amounts of phenolic estrogen. As a result of the coupling reaction, there is the formation of strong SERRS activity of azo compound. Therefore, the detection limits are as low as 0.2 × 10−4 for estrone (E1), estriol (E3), and bisphenol A (BPA). This method is universal because each SERRS fingerprint of the azo dyes a specific hormone. The use of this method is applicable for the testing of phenolic hormones through coupling reactions, and the investigation of other phenolic molecules. Therefore, this new method can be used for efficient detection. View Full-Text
Keywords: phenolic hormones; SERRS; detection phenolic hormones; SERRS; detection
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MDPI and ACS Style

Liu, Y.; Chen, Y.; Zhang, Y.; Kou, Q.; Zhang, Y.; Wang, Y.; Chen, L.; Sun, Y.; Zhang, H.; Jung, Y.M. Detection and Identification of Estrogen Based on Surface-Enhanced Resonance Raman Scattering (SERRS). Molecules 2018, 23, 1330.

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