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Molecules 2018, 23(4), 792;

Carbene Transfer Reactions Catalysed by Dyes of the Metalloporphyrin Group

Department of Chemistry & Organic Chemistry, Natural Products and Food Stuffs Unit (QOPNA), University of Aveiro, 3810-193 Aveiro, Portugal
Departamento de Química Orgânica, Universidade Federal Fluminense, Niterói 24020-150, RJ, Brazil
Departamento de Tecnologia Farmacêutica Química, Universidade Federal Fluminense, Niterói 24241-002, RJ, Brazil
Authors to whom correspondence should be addressed.
Received: 27 February 2018 / Revised: 26 March 2018 / Accepted: 27 March 2018 / Published: 29 March 2018
(This article belongs to the Special Issue Advanced Functional Dyes)


Carbene transfer reactions are very important transformations in organic synthesis, allowing the generation of structurally challenging products by catalysed cyclopropanation, cyclopropenation, carbene C-H, N-H, O-H, S-H, and Si-H insertion, and olefination of carbonyl compounds. In particular, chiral and achiral metalloporphyrins have been successfully explored as biomimetic catalysts for these carbene transfer reactions under both homogeneous and heterogeneous conditions. In this work the use of synthetic metalloporphyrins (MPorph, M = Fe, Ru, Os, Co, Rh, Ir, Sn) as homogeneous or heterogeneous catalysts for carbene transfer reactions in the last years is reviewed, almost exclusively focused on the literature since the year 2010, except when reference to older publications was deemed to be crucial. View Full-Text
Keywords: carbenes; porphyrins; metalloporphyrins; cyclopropanation; cyclopropenation; olefination; X-H insertion carbenes; porphyrins; metalloporphyrins; cyclopropanation; cyclopropenation; olefination; X-H insertion

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Simões, M.M.Q.; Gonzaga, D.T.G.; Cardoso, M.F.C.; Forezi, L.S.M.; Gomes, A.T.P.C.; da Silva, F.C.; Ferreira, V.F.; Neves, M.G.P.M.S.; Cavaleiro, J.A.S. Carbene Transfer Reactions Catalysed by Dyes of the Metalloporphyrin Group. Molecules 2018, 23, 792.

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