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Effects of the Usage of l-Cysteine (l-Cys) on Human Health

1
Biochemistry and Molecular Biology Division, Department of Agrochemistry and Biochemistry, Faculty of Science, University of Alicante, 03690 San Vicente del Raspeig, Spain
2
Department of Nutrition and Dietetics, Faculty of Health Sciences, University of Atacama, Copiapó 2862, Chile
*
Author to whom correspondence should be addressed.
Molecules 2018, 23(3), 575; https://doi.org/10.3390/molecules23030575
Received: 15 January 2018 / Revised: 27 February 2018 / Accepted: 1 March 2018 / Published: 3 March 2018
This review summarizes recent knowledge about the use of the amino acid l-Cysteine (l-Cys) through diet, nutritional supplements or drugs with the aim to improve human health or treat certain diseases. Three databases (PubMed, Scopus, and Web of Science) and different keywords have been used to create a database of documents published between 1950 and 2017 in scientific journals in English or Spanish. A total of 60,885 primary publications were ultimately selected to compile accurate information about the use of l-Cys in medicine and nutritional therapies and to identify the reported benefits of l-Cys on human health. The number of publications about the use of l-Cys for these purposes has increased significantly during the last two decades. This increase seems to be closely related to the rise of nutraceutical industries and personalized medicine. The main evidence reporting benefits of l-Cys usage is summarized. However, the lack of accurate information and studies based on clinical trials hampers consensus among authors. Thus, the debate about the role and effectiveness of supplements/drugs containing l-Cys is still open. View Full-Text
Keywords: l-cysteine; biological medicine; nutraceutical; nutritional therapy; dietary supplements l-cysteine; biological medicine; nutraceutical; nutritional therapy; dietary supplements
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Clemente Plaza, N.; Reig García-Galbis, M.; Martínez-Espinosa, R.M. Effects of the Usage of l-Cysteine (l-Cys) on Human Health. Molecules 2018, 23, 575.

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