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Molecules 2017, 22(5), 718;

Non-Chromatographic Purification of Endohedral Metallofullerenes

Department of Chemistry and Institute for Advanced Research, Nagoya University, Nagoya 464-8602, Japan
Department of Chemistry, Renmin University of China, Beijing 100872, China
Author to whom correspondence should be addressed.
Academic Editor: Kyriakos Porfyrakis
Received: 5 April 2017 / Revised: 25 April 2017 / Accepted: 26 April 2017 / Published: 29 April 2017
(This article belongs to the Special Issue Endohedral Metallofullerenes)
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The purification of endohedral metallofullerenes by high performance liquid chromatography is very time-consuming and expensive. A number of rapid and inexpensive non-chromatographic methods have thus been developed for large-scale purification of metallofullerenes. In this review, we summarize recent advances in non-chromatographic purification methods of metallofullerenes. Lewis acid-based complexation is one of the most efficient and powerful methods for separation of metallofullerenes from empty fullerenes. The first oxidation potential of metallofullerenes is a critical factor that affects the separation efficiency of the Lewis acid-based method. Supramolecular methods are effective for separation of fullerenes and metallofullerenes that are different in size and shape. Chemical/electrochemical reduction and exohedral functionalization are also utilized to separate and purify metallofullerenes on a large scale. View Full-Text
Keywords: fullerene; metallofullerene; lewis acid; complexation; cycloparapheneylene fullerene; metallofullerene; lewis acid; complexation; cycloparapheneylene

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Wang, Z.; Omachi, H.; Shinohara, H. Non-Chromatographic Purification of Endohedral Metallofullerenes. Molecules 2017, 22, 718.

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