Next Article in Journal
Systematic Identification of Machine-Learning Models Aimed to Classify Critical Residues for Protein Function from Protein Structure
Next Article in Special Issue
Chemical and Biological Research on Herbal Medicines Rich in Xanthones
Previous Article in Journal
Solid-State Form Characterization of Riparin I
Previous Article in Special Issue
Intestinal Absorption of Triterpenoids and Flavonoids from Glycyrrhizae radix et rhizoma in the Human Caco-2 Monolayer Cell Model
Article Menu
Issue 10 (October) cover image

Export Article

Open AccessArticle
Molecules 2017, 22(10), 1655;

Influence of Plant Growth Retardants on Quality of Codonopsis Radix

Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement & Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Xingke Road 723, Tianhe District, Guangzhou 510650, China
University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China
College of Food, South China Agricultural University, Wushan Road, Tianhe District, Guangzhou 510642, China
Tianfangjian (China) Pharmacy Company Ltd, 11 Xiancun Road, Tianhe District, Guangzhou 510623, China
Infinitus (China) Company Ltd, 11 Xiancun Road, Tianhe District, Guangzhou 510623, China
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Received: 8 September 2017 / Revised: 28 September 2017 / Accepted: 1 October 2017 / Published: 9 October 2017
(This article belongs to the Collection Herbal Medicine Research)
Full-Text   |   PDF [1081 KB, uploaded 9 October 2017]   |  


Plant growth retardant (PGR) refers to organics that can inhibit the cell division of plant stem tip sub-apical meristem cells or primordial meristem cell. They are widely used in the cultivation of rhizomatous functional plants; such as Codonopsis Radix, that is a famous Chinese traditional herb. However, it is still unclear whether PGR affects the medicinal quality of C. Radix. In the present study, amino acid analyses, targeted and non-targeted analyses by ultra-performance liquid chromatography combined with time-of-flight mass spectrometry (UPLC-TOF-MS) and gas chromatography-MS were used to analyze and compare the composition of untreated C. Radix and C. Radix treated with PGR. The contents of two key bioactive compounds, lobetyolin and atractylenolide III, were not affected by PGR treatment. The amounts of polysaccharides and some internal volatiles were significantly decreased by PGR treatment; while the free amino acids content was generally increased. Fifteen metabolites whose abundance were affected by PGR treatment were identified by UPLC-TOF-MS. Five of the up-regulated compounds have been reported to show immune activity, which might contribute to the healing efficacy (“buqi”) of C. Radix. The results of this study showed that treatment of C. Radix with PGR during cultivation has economic benefits and affected some main bioactive compounds in C. Radix. View Full-Text
Keywords: amino acid; Codonopsis Radix; plant growth retardant; polysaccharide; volatile amino acid; Codonopsis Radix; plant growth retardant; polysaccharide; volatile

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Liao, Y.; Zeng, L.; Li, P.; Sun, T.; Wang, C.; Li, F.; Chen, Y.; Du, B.; Yang, Z. Influence of Plant Growth Retardants on Quality of Codonopsis Radix. Molecules 2017, 22, 1655.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top