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Molecules 2016, 21(7), 943;

Two New Secondary Metabolites from the Endophytic Fungus Endomelanconiopsis endophytica

State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangdong Institute of Microbiology, Guangzhou 510070, China
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 24 May 2016 / Revised: 26 June 2016 / Accepted: 15 July 2016 / Published: 20 July 2016
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Two new secondary metabolites, endomeketals A–B (12), a new natural product (3), and a known compound (4) were isolated from the ethyl acetate extract of the endophytic fungus Endomelanconiopsis endophytica A326 derived from Ficus hirta. Their structures were determined on the basis of extensive spectroscopic analysis. All compounds were evaluated for their cytotoxic activities against SF-268, MCF-7, NCI-H460, and HepG-2 tumor cell lines. However, no compound showed cytotoxic activity against these human tumor cell lines. View Full-Text
Keywords: endophytic fungus; Endomelanconiopsis endophytica; ketals; Ficus hirta endophytic fungus; Endomelanconiopsis endophytica; ketals; Ficus hirta

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Sun, Z.-H.; Li, H.-H.; Liang, F.-L.; Chen, Y.-C.; Liu, H.-X.; Li, S.-N.; Tan, G.-H.; Zhang, W.-M. Two New Secondary Metabolites from the Endophytic Fungus Endomelanconiopsis endophytica. Molecules 2016, 21, 943.

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