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Molecules 2016, 21(4), 493;

Fruitful Decades for Canthin-6-ones from 1952 to 2015: Biosynthesis, Chemistry, and Biological Activities

College of Science, Northwest A & F University, Yangling 712100, Shaanxi, China
EaStCHEM School of Chemistry, The University of Edinburgh, The King’s Buildings, David Brewster Road, Edinburgh EH9 3FJ, UK
Authors to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 9 March 2016 / Revised: 3 April 2016 / Accepted: 6 April 2016 / Published: 15 April 2016
(This article belongs to the Section Natural Products Chemistry)
Full-Text   |   PDF [2739 KB, uploaded 15 April 2016]   |  


In this review, more than 60 natural canthin-6-one alkaloids and their structures are considered. The biosynthesis, efficient and classic synthetic approaches, and biological activities of canthin-6-one alkaloids, from 1952 to 2015, are discussed. From an analysis of their structural properties and an investigation of the literature, possible future trends for canthin-6-one alkaloids are proposed. The information reported will be helpful in future research on canthin-6-one alkaloids. View Full-Text
Keywords: canthin-6-one; biosynthesis; chemistry; biological activities canthin-6-one; biosynthesis; chemistry; biological activities

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Dai, J.; Li, N.; Wang, J.; Schneider, U. Fruitful Decades for Canthin-6-ones from 1952 to 2015: Biosynthesis, Chemistry, and Biological Activities. Molecules 2016, 21, 493.

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