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Chlorination of (Phebox)Ir(mesityl)(OAc) by Thionyl Chloride

Department of Chemistry and Chemical Biology, Rutgers New Brunswick—Busch Campus, 610 Taylor Road, Piscataway, NJ 08854, USA
Authors to whom correspondence should be addressed.
Academic Editor: Michael Findlater
Molecules 2015, 20(6), 10122-10130;
Received: 14 May 2015 / Accepted: 29 May 2015 / Published: 1 June 2015
(This article belongs to the Special Issue C-H Bond Activation and Functionalization)
Pincer (Phebox)Ir(mesityl)(OAc) (2) (Phebox = 3,5-dimethylphenyl-2,6-bis(oxazolinyl)) complex, formed by benzylic C-H activation of mesitylene (1,3,5-trimethylbenzene) using (Phebox)Ir(OAc)2OH2 (1), was treated with thionyl chloride to rapidly form 1-(chloromethyl)-3,5-dimethylbenzene in 50% yield at 23 °C. A green species was obtained at the end of reaction, which decomposed during flash column chromatography to form (Phebox)IrCl2OH2 in 87% yield. View Full-Text
Keywords: chlorination; phebox ligand; iridium mesityl; thionyl chloride; pincer complex chlorination; phebox ligand; iridium mesityl; thionyl chloride; pincer complex
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MDPI and ACS Style

Zhou, M.; Goldman, A.S. Chlorination of (Phebox)Ir(mesityl)(OAc) by Thionyl Chloride. Molecules 2015, 20, 10122-10130.

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