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Molecules 2015, 20(5), 9029-9053;

Protein-Carbohydrate Interactions as Part of Plant Defense and Animal Immunity

Lab Biochemistry and Glycobiology, Department of Molecular Biotechnology, Ghent University, Coupure links 653, B-9000 Ghent, Belgium
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 7 April 2015 / Revised: 12 May 2015 / Accepted: 14 May 2015 / Published: 19 May 2015
(This article belongs to the Special Issue Protein-Carbohydrate Interactions, and Beyond)
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The immune system consists of a complex network of cells and molecules that interact with each other to initiate the host defense system. Many of these interactions involve specific carbohydrate structures and proteins that specifically recognize and bind them, in particular lectins. It is well established that lectin-carbohydrate interactions play a major role in the immune system, in that they mediate and regulate several interactions that are part of the immune response. Despite obvious differences between the immune system in animals and plants, there are also striking similarities. In both cases, lectins can play a role as pattern recognition receptors, recognizing the pathogens and initiating the stress response. Although plants do not possess an adaptive immune system, they are able to imprint a stress memory, a mechanism in which lectins can be involved. This review will focus on the role of lectins in the immune system of animals and plants. View Full-Text
Keywords: lectin; carbohydrate; plant defense; animal immunity lectin; carbohydrate; plant defense; animal immunity

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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De Schutter, K.; Van Damme, E.J.M. Protein-Carbohydrate Interactions as Part of Plant Defense and Animal Immunity. Molecules 2015, 20, 9029-9053.

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