Next Article in Journal
Evaluation of Novel Antibacterial N-Halamine Nanoparticles Prodrugs towards Susceptibility of Escherichia coli Induced by DksA Protein
Next Article in Special Issue
Special Issue: Practical Applications of Metal Complexes
Previous Article in Journal
Bifunctionalized Allenes. Part XVI. Synthesis of 3-Phosphoryl-2,5-dihydrofurans by Coinage Metal-Catalyzed Cyclo-isomerization of Phosphorylated α-Hydroxyallenes
Previous Article in Special Issue
Cellular Transport Mechanisms of Cytotoxic Metallodrugs: An Overview beyond Cisplatin
Open AccessArticle

Photorelease of Pyridyl Esters in Organometallic Ru(II) Arene Complexes

1
CIC biomaGUNE, Donostia–San Sebastián 20009, Spain
2
IKERBASQUE, Basque Foundation for Science, Bilbao 48011, Spain
3
Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK
4
Department of Chemistry and NIS Centre of Excellence, University of Turin, Turin 10125, Italy
5
Kimika Fakultatea, Euskal Herriko Unibertsitatea and Donostia International Physics Center (DIPC), Donostia–San Sebastián 20080, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Iztok Turel
Molecules 2015, 20(4), 7276-7291; https://doi.org/10.3390/molecules20047276
Received: 20 February 2015 / Revised: 14 April 2015 / Accepted: 15 April 2015 / Published: 21 April 2015
(This article belongs to the Special Issue Practical Applications of Metal Complexes)
New Ru(II) arene complexes of formula [(η6-p-cym)Ru(N-N)(X)]2+ (where p-cym = para-cymene, N-N = 2,2'-bipyrimidine (bpm) or 2,2'-bipyridine (bpy) and X = m/p-COOMe-Py, 14) were synthesised and characterized, including the molecular structure of complexes [(η6-p-cym)Ru(bpy)(m-COOMe-Py)]2+ (3) and [(η6-p-cym)Ru(bpy) (p-COOMe-Py)]2+ (4) by single-crystal X-ray diffraction. Complexes 14 are stable in the dark in aqueous solution over 48 h and photolysis studies indicate that they can photodissociate the monodentate m/p-COOMe-Py ligands selectively with yields lower than 1%. DFT and TD-DFT calculations (B3LYP/LanL2DZ/6-31G**) performed on singlet and triplet states pinpoint a low-energy triplet state as the reactive state responsible for the selective dissociation of the monodentate pyridyl ligands. View Full-Text
Keywords: photoactivatable complexes; ruthenium; ruthenium arene; PDT; DFT; photochemistry photoactivatable complexes; ruthenium; ruthenium arene; PDT; DFT; photochemistry
Show Figures

Graphical abstract

MDPI and ACS Style

Habtemariam, A.; Garino, C.; Ruggiero, E.; Alonso-de Castro, S.; Mareque-Rivas, J.C.; Salassa, L. Photorelease of Pyridyl Esters in Organometallic Ru(II) Arene Complexes. Molecules 2015, 20, 7276-7291.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop