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Open AccessArticle

Bioactive Constituents from the Aerial Parts of Lippia triphylla

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Tianjin State Key Laboratory of Modern Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China
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Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshan Road, Nankai District, Tianjin 300193, China
*
Author to whom correspondence should be addressed.
Academic Editor: Christopher W. K. Lam
Molecules 2015, 20(12), 21946-21959; https://doi.org/10.3390/molecules201219814
Received: 27 September 2015 / Revised: 27 November 2015 / Accepted: 4 December 2015 / Published: 8 December 2015
(This article belongs to the Collection Herbal Medicine Research)
Five new compounds, lippianosides A (1), B (2), C (3), D (4), and E (5), along with 26 (631) known ones were obtained from the 95% EtOH extract of Lippia triphylla (L. triphylla) aerial parts collected from Rwanda, Africa. Among the known compounds, 11 and 1730 were isolated from the Lippia genus for the first time. In addition, 12, 13, and 16 were firstly obtained from this species. The structures of them were elucidated by chemical and spectroscopic methods. The antioxidant and triglyceride accumulation inhibition effects of the 31 compounds were examined in L6 cells and HepG2 cells, respectively. View Full-Text
Keywords: Lippia triphylla; lippianoside; structure elucidation; antioxidant; triglyceride accumulation inhibition; L6 cells; HepG2 cells Lippia triphylla; lippianoside; structure elucidation; antioxidant; triglyceride accumulation inhibition; L6 cells; HepG2 cells
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Zhang, Y.; Chen, Y.; Wang, S.; Dong, Y.; Wang, T.; Qu, L.; Li, N.; Wang, T. Bioactive Constituents from the Aerial Parts of Lippia triphylla. Molecules 2015, 20, 21946-21959.

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