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Molecules 2015, 20(10), 18095-18106;

Characterization of Non-Anthocyanic Flavonoids in Some Hybrid Red Grape Extracts Potentially Interesting for Industrial Uses

Consiglio per la Ricerca in Agricoltura e l'Analisi dell'Economia Agraria—Centro di Ricerca per la Viticoltura (CREA-VIT), Viale XXVIII Aprile 26, Conegliano (TV) 31015, Italy
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Academic Editor: Maurizio Battino
Received: 7 August 2015 / Revised: 24 September 2015 / Accepted: 30 September 2015 / Published: 2 October 2015
(This article belongs to the Section Natural Products Chemistry)
Full-Text   |   PDF [717 KB, uploaded 2 October 2015]   |  


Previous studies showed that hybrid grapes often have qualitatively and quantitatively higher polyphenolic contents than the common V. vinifera grape varieties. In general, these compounds are studied for grape chemotaxonomy and for nutraceutical purposes due to their relevant antioxidant activity. Non-anthocyanic flavonoid composition of five red hybrid grape varieties produced by crossing of V. vinifera, V. aestivalis, V. cinerea, V. berlandieri, V. labrusca, V. lincecumii, and V. rupestris were studied by liquid chromatography/high-resolution mass spectrometry. Thirty-one compounds were identified, including methylnaringenin, a tetrahydroxy-dimethoxyflavanone-hexoside, two flavonols (quercetin and a pentahydroxyflavone isomer), 20 glycoside flavonols (four quercetin, two myricetin, two kaempferol, three isorhamnetin, one laricitrin, two syringetin, one kaempferide and two dihydroflavonol derivatives; myricetin-glucoside-glucuronide; myricetin-diglucoside; syringetin-dihexoside), three flavan-3-ols (−)-epicatechin, (+)-catechin, (−)-epicatechin gallate) and four proantocyanidins (procyanidin B1, procyanidin B2, procyanidin B3 or B4/B5, procyanidin T2 or T3/T4/C1). Seibel 19881, Seyve Villard 12-347 and Seyve Villard 29-399 were particularly rich in polyphenols. These findings emphasize that these grapes are especially interesting for the production of antioxidant extracts for nutraceutical and pharmaceutical uses. View Full-Text
Keywords: antioxidants; hybrid grapes; polyphenols; high-resolution mass spectrometry antioxidants; hybrid grapes; polyphenols; high-resolution mass spectrometry

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De Rosso, M.; Panighel, A.; Vedova, A.D.; Gardiman, M.; Flamini, R. Characterization of Non-Anthocyanic Flavonoids in Some Hybrid Red Grape Extracts Potentially Interesting for Industrial Uses. Molecules 2015, 20, 18095-18106.

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