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Molecules 2015, 20(1), 1551-1559;

New Sesquiterpenoids and a Diterpenoid from Alpinia oxyphylla

Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China
The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
Authors to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 4 December 2014 / Accepted: 31 December 2014 / Published: 16 January 2015
(This article belongs to the Section Natural Products Chemistry)
Full-Text   |   PDF [753 KB, uploaded 16 January 2015]   |  


The new compounds 2-methyl-6-isopropyl-7-hydroxymethyl naphthalene (1), oxyphyllenone H (2), epi-oxyphyllenone (6), (E)-labda-12,14-dien-15(16)-olide-17-oic acid (3), and two new natural products 4 and 5 were isolated from the ethyl acetate part of 95% ethanol extract of Alpinia oxyphylla, together with six known compounds 712. The inhibitory effects of compounds 112 on α-glucosidase were evaluated, and compounds 1, 3 and 6 showed moderate bioactive effect, with inhibitory rates of 10.3%, 10.0% and 11.5%, respectively, compared to the positive control acarbose (41.9%) at 20 µg/mL. View Full-Text
Keywords: Alpinia oxyphylla; sesquiterpenoids; diterpenoid Alpinia oxyphylla; sesquiterpenoids; diterpenoid

Figure 1

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Hou, L.; Ding, G.; Guo, B.; Huang, W.; Zhang, X.; Sun, Z.; Shi, X. New Sesquiterpenoids and a Diterpenoid from Alpinia oxyphylla. Molecules 2015, 20, 1551-1559.

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