Anti-Inflammatory Effects of Total Isoflavones from Pueraria lobata on Cerebral Ischemia in Rats
Abstract
:1. Introduction
2. Results and Discussion
2.1. Compositional Analysis of Total Isoflavones from P. lobata Extracts
Isoflavones | Concentration (%, w/w) |
---|---|
Puerarin | 7.2 |
Daidzin | 3.8 |
Genistin | 1.5 |
Total isoflavones | 12.5 |
2.2. Effect on Infarct Volume in MCAo Rats
2.3. Effects on COX-2, GFAP and OX-42 Expression
2.4. Discussion
3. Experimental
3.1. Preparation of Total Isoflavones from P. lobata Extracts
3.2. Animals and Treatments
3.3. Tissue Preparation
3.4. Measurement of Infarct Volume
3.5. Immunohistochemistry
3.6. Statistical Analysis
4. Conclusions
Acknowledgments
Conflicts of Interest
References
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Lim, D.W.; Lee, C.; Kim, I.-H.; Kim, Y.T. Anti-Inflammatory Effects of Total Isoflavones from Pueraria lobata on Cerebral Ischemia in Rats. Molecules 2013, 18, 10404-10412. https://doi.org/10.3390/molecules180910404
Lim DW, Lee C, Kim I-H, Kim YT. Anti-Inflammatory Effects of Total Isoflavones from Pueraria lobata on Cerebral Ischemia in Rats. Molecules. 2013; 18(9):10404-10412. https://doi.org/10.3390/molecules180910404
Chicago/Turabian StyleLim, Dong Wook, Changho Lee, In-Ho Kim, and Yun Tai Kim. 2013. "Anti-Inflammatory Effects of Total Isoflavones from Pueraria lobata on Cerebral Ischemia in Rats" Molecules 18, no. 9: 10404-10412. https://doi.org/10.3390/molecules180910404
APA StyleLim, D. W., Lee, C., Kim, I.-H., & Kim, Y. T. (2013). Anti-Inflammatory Effects of Total Isoflavones from Pueraria lobata on Cerebral Ischemia in Rats. Molecules, 18(9), 10404-10412. https://doi.org/10.3390/molecules180910404