New Resveratrol Oligomer Derivatives from the Roots of Rheum lhasaense
Abstract
:1. Introduction
2. Results and Discussion
2.1. Structural Elucidation of the New Compounds
Positions | 1 | 2 | ||||
---|---|---|---|---|---|---|
δH (mult, J in Hz, I) | δC | ROSEY | δH (mult, J in Hz, I) | δC | ROSEY | |
1a | 134.2 | 134.3 | ||||
2a(6a) | 7.12 (d, 8.5, 2H) | 128.1 | 7a, 8a | 7.13 (d, 8.5, 2H) | 128.1 | 7a, 8a |
3a(5a) | 6.77 (d, 8.5, 2H) | 116.3 | 6.76 (d, 8.5, 2H) | 116.3 | ||
4a | 158.5 | 158.4 | ||||
7a | 5.28 (d, 5.4, 1H) | 94.5 | 5.30 (d, 5.4, 1H) | 94.5 | ||
8a | 4.31 (d, 5.4, 1H) | 56.7 | 4.33 (d, 5.4, 1H) | 56.6 | ||
9a | 146.5 | 146.6 | ||||
10a(14a) | 6.10 (d, 2.0 Hz, 2H) | 107.1 | 7a, 8a | 6.13 (d, 1.7 ,2H) | 107.0 | 7a, 8a |
11a(13a) | 159.6 | 159.6 | ||||
12a | 6.14 (t, 2.0 Hz, 1H) | 102.0 | 6.16 (t, 1.7, 1H) | 102.0 | ||
1b | 141.2 | 141.5 | ||||
2b | 6.34 (s, 1H) | 110.1 | 6.50 (s, 1H) | 108.0 | ||
3b | 155.5 | 155.6 | ||||
4b | 115.1 | 115.4 | ||||
5b | 163.0 | 163.3 | ||||
6b | 6.32 (s, 1H) | 102.5 | 6.60 (s, 1H) | 99.6 | ||
7b | 6.40 (d, 12.2, 1H) | 129.8 | 8b | 6.85 (d, 16.2, 1H) | 127.4 | |
8b | 6.46 (d, 12.2, 1H) | 131.0 | 7b | 7.02 (d, 16.2, 1H) | 129.3 | |
9b | 131.7 | 132.3 | ||||
10b | 6.94 (br s, 1H) | 127.4 | 7.20 (br s, 1H) | 124.1 | ||
11b | 131.7 | 132.4 | ||||
12b | 160.4 | 160.9 | ||||
13b | 6.74 (d, 8.0, 1H) | 109.8 | 6.84 (d, 8.3, 1H) | 110.3 | ||
14b | 7.21 (d, 8.0, 1H) | 130.6 | 7.37 (d, 8.3, 1H) | 128.7 | ||
1c | 132.9 | 132.8 | ||||
2c(6c) | 7.16 (d, 8.5, 2H) | 128.7 | 7c, 8c | 7.17 (d, 8.5, 2H) | 128.7 | 7c, 8c |
3c(5c) | 6.75 (d, 8.5, 2H) | 116.3 | 6.79 (d, 8.5, 2H) | 116.3 | ||
4c | 158.7 | 158.6 | ||||
7c | 5.36 (d, 8.3, 1H) | 94.7 | 8c | 5.39 (d, 8.4, 1H) | 94.9 | 8c |
8c | 4.36 (d, 8.3, 1H) | 58.7 | 7c, 10b | 4.40 (d, 8.4, 1H) | 58.7 | 7c, 10b |
9c | 145.4 | 145.3 | ||||
10c(14c) | 6.10 (d, 2.0, 2H) | 107.7 | 7c, 8c | 6.15 (d, 1.7, 2H) | 107.9 | 7c, 8c |
11c(13c) | 159.8 | 159.8 | ||||
12c | 6.17 (t, 2.0, 1H) | 102.5 | 6.22 (t, 1.7, 1H) | 102.5 |
2.2. Antioxidant Activities by DPPH Scavenging Capacities
Compds. | DPPH radical IC50 (μM) a |
---|---|
1 | 49.7 ± 2.3 |
2 | 31.3 ± 1.5 |
3 | 28.7 ± 1.0 |
4 | 69.8 ± 2.3 |
5 | 52.6 ± 1.1 |
6 | 190.2 ± 3.8 |
Vitamin E | 27.9 ± 0.9 |
3. Experimental
3.1. General
3.2. Plant Materials
3.3. Extraction and Isolation of the Compounds
3.4. Spectroscopic Data
3.5. DPPH Assays
4. Conclusions
Acknowledgments
Conflicts of Interest
References
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Liu, W.-B.; Hu, L.; Hu, Q.; Chen, N.-N.; Yang, Q.-S.; Wang, F.-F. New Resveratrol Oligomer Derivatives from the Roots of Rheum lhasaense. Molecules 2013, 18, 7093-7102. https://doi.org/10.3390/molecules18067093
Liu W-B, Hu L, Hu Q, Chen N-N, Yang Q-S, Wang F-F. New Resveratrol Oligomer Derivatives from the Roots of Rheum lhasaense. Molecules. 2013; 18(6):7093-7102. https://doi.org/10.3390/molecules18067093
Chicago/Turabian StyleLiu, Wen-Bo, Lin Hu, Qun Hu, Na-Na Chen, Qing-Song Yang, and Fang-Fang Wang. 2013. "New Resveratrol Oligomer Derivatives from the Roots of Rheum lhasaense" Molecules 18, no. 6: 7093-7102. https://doi.org/10.3390/molecules18067093