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Molecules 2012, 17(8), 9220-9230; https://doi.org/10.3390/molecules17089220

Cyclization-Carbonylation-Cyclization Coupling Reaction of Propargyl Ureas with Palladium(II)-Bisoxazoline Catalyst

1
Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan
2
School of Pharmacy, Nihon Pharmaceutical University, 10281, Komuro, Inamachi, Kita-Adachigun, Saitama 362-0806, Japan
*
Authors to whom correspondence should be addressed.
Received: 16 July 2012 / Revised: 30 July 2012 / Accepted: 31 July 2012 / Published: 2 August 2012
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Abstract

The cyclization-carbonylation-cyclization coupling reaction (CCC-coupling reaction) of propargyl ureas catalyzed by PdII(box) complexes afforded symmetrical ketones bearing two 2-amino-2-oxazoline groups in good to moderate yields. View Full-Text
Keywords: CCC-coupling; bisoxazoline; palladium; carbonylation; propargyl urea CCC-coupling; bisoxazoline; palladium; carbonylation; propargyl urea
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Kusakabe, T.; Kawaguchi, K.; Kawamura, M.; Niimura, N.; Shen, R.; Takayama, H.; Kato, K. Cyclization-Carbonylation-Cyclization Coupling Reaction of Propargyl Ureas with Palladium(II)-Bisoxazoline Catalyst. Molecules 2012, 17, 9220-9230.

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