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Article

Oxime-Based Carbonates as Useful Reagents for Both N-Protection and Peptide Coupling

1
Department of Chemistry, Faculty of Science, Alexandria University, P.O. Box 426, Ibrahimia, 21321 Alexandria, Egypt
2
Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, 11451 Riyadh, Saudi Arabia
3
Department of Chemistry and Molecular Pharmacology, Institute for Research in Biomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028 Barcelona, Spain
4
CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028 Barcelona, Spain
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Department of Organic Chemistry, University of Barcelona, Martí i Franqués 1-11, 08028 Barcelona, Spain
6
School of Chemistry, University of KwaZulu-Natal, 4041 Durban, South Africa
*
Authors to whom correspondence should be addressed.
Molecules 2012, 17(12), 14361-14376; https://doi.org/10.3390/molecules171214361
Received: 22 October 2012 / Revised: 23 November 2012 / Accepted: 30 November 2012 / Published: 5 December 2012
(This article belongs to the Special Issue Chemical Protein and Peptide Synthesis)
We have demonstrated that oxime-based mixed carbonates are very effective reagents for both N-protection and peptide coupling. View Full-Text
Keywords: oxime; additives; N-protection; activation; coupling; peptide oxime; additives; N-protection; activation; coupling; peptide
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MDPI and ACS Style

Jad, Y.E.-S.; Khattab, S.N.; El-Faham, A.; Albericio, F. Oxime-Based Carbonates as Useful Reagents for Both N-Protection and Peptide Coupling. Molecules 2012, 17, 14361-14376. https://doi.org/10.3390/molecules171214361

AMA Style

Jad YE-S, Khattab SN, El-Faham A, Albericio F. Oxime-Based Carbonates as Useful Reagents for Both N-Protection and Peptide Coupling. Molecules. 2012; 17(12):14361-14376. https://doi.org/10.3390/molecules171214361

Chicago/Turabian Style

Jad, Yahya E.-S., Sherine N. Khattab, Ayman El-Faham, and Fernando Albericio. 2012. "Oxime-Based Carbonates as Useful Reagents for Both N-Protection and Peptide Coupling" Molecules 17, no. 12: 14361-14376. https://doi.org/10.3390/molecules171214361

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