Next Article in Journal
Efficient Preparation of α-Ketoacetals
Previous Article in Journal
Influence of Nonpolar Substances on the Extraction Efficiency of Six Alkaloids in Zoagumhwan Investigated by Ultra Performance Liquid Chromatography and Photodiode Array Detection
Open AccessArticle

An Efficient One-Pot Synthesis of Pyrano[3,2-c]quinolin-2,5-dione Derivatives Catalyzed by L-Proline

by Songlei Zhu 1,2,*,†, Jing Wang 2,†, Zhou Xu 2 and Jie Li 3
1
Key Laboratory of Biological Cancer Therapy of Jiangsu Province, Xuzhou Medical College, Xuzhou 221004, China
2
Department of Chemistry, Xuzhou Medical College, Xuzhou 221004, China
3
School of Pharmacy, Xuzhou Medical College, Xuzhou 221004, China
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Molecules 2012, 17(12), 13856-13863; https://doi.org/10.3390/molecules171213856
Received: 5 November 2012 / Revised: 17 November 2012 / Accepted: 20 November 2012 / Published: 22 November 2012
(This article belongs to the Section Organic Chemistry)
A series of 4-aryl-6-methyl-3,4-dihydro-2H-pyrano[3,2-c]quinolin-2,5(6H)-diones were synthesized via the three-component reactions of aromatic aldehydes, 4-hydroxy-1-methylquinolin-2(1H)-one, and Meldrum’s acid catalyzed by L-proline. The structures of the products were identified by spectroscopic analysis. A mechanism for this three-component reaction catalyzed by L-proline was proposed. View Full-Text
Keywords: pyrano[3,2-c]quinolin-2,5(6H)-dione; multi-component reaction; L-proline pyrano[3,2-c]quinolin-2,5(6H)-dione; multi-component reaction; L-proline
Show Figures

Figure 1

MDPI and ACS Style

Zhu, S.; Wang, J.; Xu, Z.; Li, J. An Efficient One-Pot Synthesis of Pyrano[3,2-c]quinolin-2,5-dione Derivatives Catalyzed by L-Proline. Molecules 2012, 17, 13856-13863.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop