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Volume 17
Issue 11
10.3390/molecules171113175
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Article

Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2

by
Rong Wang
†,
Tian-Mi Liu
†,
Ming-Hui Shen
,
Ming-Qiu Yang
,
Quan-Ying Feng
,
Xian-Ming Tang
and
Xiang-Min Li
*
Hainan Provincial Fisheries Research Institute, Haikou 570203, Hainan, China
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Molecules 2012, 17(11), 13175-13182; https://doi.org/10.3390/molecules171113175
Received: 18 October 2012 / Revised: 30 October 2012 / Accepted: 31 October 2012 / Published: 5 November 2012
(This article belongs to the Section Natural Products Chemistry)
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Abstract

Three new γ-butenolide derivatives 1–3, named spiculisporic acids B–D, were isolated from the culture of Aspergillus sp. HDf2, a marine-derived fungus that resides in the sea urchin, Anthocidaris crassispina. The structures of 1–3 were elucidated on the basis of spectroscopic methods, including MS and 2D NMR techniques. Their in vitro cytotoxic activities against two cell lines (SGC-7901, human gastric adenocarcinoma and SPC-A-1, human lung adenocarcinoma) and inhibitory activities against Staphylococcus aureus ATCC 51650 were investigated. View Full-Text
Keywords: γ-butenolide derivatives; spiculisporic acids B–D; Aspergillus sp.; marine fungus γ-butenolide derivatives; spiculisporic acids B–D; Aspergillus sp.; marine fungus
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MDPI and ACS Style

Wang, R.; Liu, T.-M.; Shen, M.-H.; Yang, M.-Q.; Feng, Q.-Y.; Tang, X.-M.; Li, X.-M. Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2. Molecules 2012, 17, 13175-13182. https://doi.org/10.3390/molecules171113175

AMA Style

Wang R, Liu T-M, Shen M-H, Yang M-Q, Feng Q-Y, Tang X-M, Li X-M. Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2. Molecules. 2012; 17(11):13175-13182. https://doi.org/10.3390/molecules171113175

Chicago/Turabian Style

Wang, Rong, Tian-Mi Liu, Ming-Hui Shen, Ming-Qiu Yang, Quan-Ying Feng, Xian-Ming Tang, and Xiang-Min Li. 2012. "Spiculisporic Acids B–D, Three New γ-Butenolide Derivatives from a Sea Urchin-Derived Fungus Aspergillus sp. HDf2" Molecules 17, no. 11: 13175-13182. https://doi.org/10.3390/molecules171113175

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