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Open AccessArticle

Fast Method for Synthesis of Alkyl and Aryl-N-Methylnitrones

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Chemistry Department, Faculty of Science, Gazi University, Ankara 06500, Turkey
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Chemistry Department, Faculty of Science, Çankırı Karatekin University, Çankırı 18100, Turkey
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Chemistry Department, Faculty of Science and Arts, Hitit University, Çorum 19030, Turkey
*
Author to whom correspondence should be addressed.
Molecules 2011, 16(8), 6677-6683; https://doi.org/10.3390/molecules16086677
Received: 20 June 2011 / Revised: 18 July 2011 / Accepted: 19 July 2011 / Published: 8 August 2011
A simple, fast, efficient and eco-friendly procedure was developed for the synthesis of alkyl and aryl-N-methylnitrones. The corresponding nitrones of aromatic aldehydes, aliphatic aldehydes and alicyclic carbonyl compounds were prepared from N-methylhydroxylamine hydrochloride and Na2CO3-Na2SO4 by simply grinding at room temperature without using solvent. View Full-Text
Keywords: nitrone; grinding; solid-phase synthesis; solventless nitrone; grinding; solid-phase synthesis; solventless
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MDPI and ACS Style

Yavuz, S.; Ozkan, H.; Colak, N.; Yildirir, Y. Fast Method for Synthesis of Alkyl and Aryl-N-Methylnitrones. Molecules 2011, 16, 6677-6683.

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