Next Article in Journal
Antioxidant Compounds from Propolis Collected in Anhui, China
Previous Article in Journal
Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents
 
Search for Articles:
Title / Keyword
Author / Affiliation
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
Journals
Molecules
Volume 16
Issue 4
10.3390/molecules16043433
molecules-logo
Submit to this Journal Review for this Journal Edit a Special Issue
► Article Menu

Article Menu

share announcement thumb_up
...
textsms
...
Open AccessArticle

Antioxidant, Total Phenolic Content and Cytotoxicity Evaluation of Selected Malaysian Plants

by
Suhailah Wasman Qader
1,*,
Mahmood Ameen Abdulla
2,
Lee Suan Chua
3,
Nigar Najim
4,
Mazatulikhma Mat Zain
4 and
Salehhuddin Hamdan
1
1
Department of Biological Science, Faculty of Biosciences and Bioengineering, University of Technology Malaysia, 81310, UTM Skudai, Johor, Malaysia
2
Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia
3
Metabolites Profiling Laboratory, Chemical Engineering Pilot Plant, University Technology Malaysia, 81310, UTM Skudai, Johor, Malaysia
4
Tissue Culture Research Laboratory, Centre of Synthesis and Chemical Biology, Institute of Science, University Technology MARA, 40450, Shah Alam, Malaysia
*
Author to whom correspondence should be addressed.
Molecules 2011, 16(4), 3433-3443; https://doi.org/10.3390/molecules16043433
Received: 28 February 2011 / Revised: 2 April 2011 / Accepted: 8 April 2011 / Published: 21 April 2011
(This article belongs to the Section Natural Products Chemistry)
View Full-Text Download PDF
Browse Figures

Abstract

Aqueous and ethanol extracts of different traditional Malaysian plants (Polygonum minus, Andrographis paniculata, Curcuma xanthorrhiza, Momordica charantia and Strobilanthes crispus) were evaluated for their antioxidant properties, total phenolic content and cytotoxic activity. Antioxidant activity was evaluated by using 1,1-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays. The results showed that ethanol extracts contain high antioxidant activities compared to aqueous extracts. The findings exhibited a strong correlation between antioxidant activity and the total phenol contents. In addition, all the plant extracts showed non-toxic effects against a normal human lung fibroblast cell line (Hs888Lu). Although traditionally aqueous extracts are used, we determined that ethanol extracts usually achieved better activity in the assays. View Full-Text
Keywords: antioxidant activity; total phenolic content; cytotoxicity; Malaysian plants antioxidant activity; total phenolic content; cytotoxicity; Malaysian plants
►▼ Show Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License
SciFeed

Share and Cite

MDPI and ACS Style

Qader, S.W.; Abdulla, M.A.; Chua, L.S.; Najim, N.; Zain, M.M.; Hamdan, S. Antioxidant, Total Phenolic Content and Cytotoxicity Evaluation of Selected Malaysian Plants. Molecules 2011, 16, 3433-3443. https://doi.org/10.3390/molecules16043433

AMA Style

Qader SW, Abdulla MA, Chua LS, Najim N, Zain MM, Hamdan S. Antioxidant, Total Phenolic Content and Cytotoxicity Evaluation of Selected Malaysian Plants. Molecules. 2011; 16(4):3433-3443. https://doi.org/10.3390/molecules16043433

Chicago/Turabian Style

Qader, Suhailah Wasman; Abdulla, Mahmood Ameen; Chua, Lee Suan; Najim, Nigar; Zain, Mazatulikhma Mat; Hamdan, Salehhuddin. 2011. "Antioxidant, Total Phenolic Content and Cytotoxicity Evaluation of Selected Malaysian Plants" Molecules 16, no. 4: 3433-3443. https://doi.org/10.3390/molecules16043433

Find Other Styles

Article Metrics

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop