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Open AccessArticle

DNA-Templated Preparation of Gold Nanoparticles

Department of Chemical and Biochemical Engineering, Chosun University, Gwangju, 501-759, South Korea
Department of Chemistry, Korea University, Seoul, 136-701, South Korea
Authors to whom correspondence should be addressed.
Molecules 2011, 16(10), 8143-8151;
Received: 6 September 2011 / Revised: 19 September 2011 / Accepted: 20 September 2011 / Published: 27 September 2011
(This article belongs to the Special Issue DNA-Templated Synthesis)
DNA-mediated gold nanoparticles were prepared by chemical reduction of DNA-Au(III) complex. The DNA-Au(III) was first formed by reacting DNA with HAuCl4 at a pH of 5.6. The complex in solution was reacted with hydrazine reducing Au(III) to Au. The reduced Au formed nanodimensional aggregates. The particle distributions were obtained by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). This method resulted in a rather uniform dispersion of Au nanoparticles of near-spherical shape and 45~80 nm in diameter. Gold nanoparticles were embedded and stabilized by DNA. View Full-Text
Keywords: DNA-Au complexes; DNA-mediated; gold nanoparticles DNA-Au complexes; DNA-mediated; gold nanoparticles
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Sohn, J.S.; Kwon, Y.W.; Jin, J.I.; Jo, B.W. DNA-Templated Preparation of Gold Nanoparticles. Molecules 2011, 16, 8143-8151.

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