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Open AccessArticle

Copper-Catalyzed N-Arylation of Amides Using (S)-N-Methylpyrrolidine-2-carboxylate as the Ligand

1
College of Chemical Engineering and Material, Heilongjiang University, Haerbin 150080, China
2
Mudanjiang Normal University, Mudanjiang 157012, China
*
Author to whom correspondence should be addressed.
Molecules 2010, 15(3), 1154-1160; https://doi.org/10.3390/molecules15031154
Received: 23 January 2010 / Revised: 25 February 2010 / Accepted: 2 March 2010 / Published: 2 March 2010
(S)-N-methylpyrrolidine-2-carboxylate, a derivative of natural L-proline, was found to be an efficient ligand for the copper-catalyzed Goldberg-type N-arylation of amides with aryl halides under mild conditions. A variety of N-arylamides were synthesized in good to high yields. View Full-Text
Keywords: copper; (S)-N-methylpyrrolidine-2-carboxylate; arylations; amides copper; (S)-N-methylpyrrolidine-2-carboxylate; arylations; amides
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MDPI and ACS Style

Wang, C.; Liu, L.; Wang, W.; Ma, D.-S.; Zhang, H. Copper-Catalyzed N-Arylation of Amides Using (S)-N-Methylpyrrolidine-2-carboxylate as the Ligand. Molecules 2010, 15, 1154-1160. https://doi.org/10.3390/molecules15031154

AMA Style

Wang C, Liu L, Wang W, Ma D-S, Zhang H. Copper-Catalyzed N-Arylation of Amides Using (S)-N-Methylpyrrolidine-2-carboxylate as the Ligand. Molecules. 2010; 15(3):1154-1160. https://doi.org/10.3390/molecules15031154

Chicago/Turabian Style

Wang, Chaoyu; Liu, Lijuan; Wang, Wei; Ma, Dong-Sheng; Zhang, Hua. 2010. "Copper-Catalyzed N-Arylation of Amides Using (S)-N-Methylpyrrolidine-2-carboxylate as the Ligand" Molecules 15, no. 3: 1154-1160. https://doi.org/10.3390/molecules15031154

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