Next Article in Journal
Antioxidant Activities of Total Phenols of Prunella vulgaris L. in Vitro and in Tumor-bearing Mice
Previous Article in Journal
Structural Relationship and Binding Mechanisms of Five Flavonoids with Bovine Serum Albumin
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Molecules
Volume 15
Issue 12
10.3390/molecules15129135
molecules-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Unexplored Nucleophilic Ring Opening of Aziridines †

by
Ana María Costero
1,2,
Salvador Gil
1,2,
Margarita Parra
1,2,* and
Pablo Rodríguez
2
1
Instituto de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Centro Mixto Universidad Politécnica de Valencia, Universidad de Valencia, 46100 Burjassot, Spain
2
Department de Organic Chemistry, Universitat de València, Dr. Moliner 50, 46100 Burjassot, Spain
*
Author to whom correspondence should be addressed.
†
Dedicated to Professor Carmen Nájera on occasion of her 60th birthday.
Molecules 2010, 15(12), 9135-9144; https://doi.org/10.3390/molecules15129135
Submission received: 24 November 2010 / Revised: 1 December 2010 / Accepted: 6 December 2010 / Published: 10 December 2010
Browse Figures
Versions Notes

Abstract

The reactivity of dianions of carboxylic acids towards aziridines has been studied. Although, a similar reactivity to that of enolates from ketones, esters or amides has been observed, the method directly yields g-aminoacids in one step. The method is complementary of previous results of enenediolate reactivity with other electrophiles. A comparative study with the reactivity of this enediolates with epoxides is included.
Keywords: enediolate; regioselectivity; diastereoselectivity; aziridines; g-aminoacids enediolate; regioselectivity; diastereoselectivity; aziridines; g-aminoacids
Graphical Abstract

Share and Cite

MDPI and ACS Style

Costero, A.M.; Gil, S.; Parra, M.; Rodríguez, P. Unexplored Nucleophilic Ring Opening of Aziridines. Molecules 2010, 15, 9135-9144. https://doi.org/10.3390/molecules15129135

AMA Style

Costero AM, Gil S, Parra M, Rodríguez P. Unexplored Nucleophilic Ring Opening of Aziridines. Molecules. 2010; 15(12):9135-9144. https://doi.org/10.3390/molecules15129135

Chicago/Turabian Style

Costero, Ana María, Salvador Gil, Margarita Parra, and Pablo Rodríguez. 2010. "Unexplored Nucleophilic Ring Opening of Aziridines" Molecules 15, no. 12: 9135-9144. https://doi.org/10.3390/molecules15129135

APA Style

Costero, A. M., Gil, S., Parra, M., & Rodríguez, P. (2010). Unexplored Nucleophilic Ring Opening of Aziridines. Molecules, 15(12), 9135-9144. https://doi.org/10.3390/molecules15129135

Article Metrics

Back to TopTop