Correction to Oz, H.S.; Ebersole, Jeffrey L. Application of Prodrugs to Inflammatory Diseases of the Gut. Molecules 2008, 13, 452-474
Still in an exploratory stage, recently an amino acid (mutual) azo prodrug of 5-ASA was prepared for targeted drug delivery to the inflamed colonic tissue in IBD by coupling L-tryptophan with salicylic acid, [56]. The synthesized prodrug was found to be as effective as sulfasalazine in attenuating colitis in a TNBS-induced rat model without the ulceration side effects of 5-ASA.
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Oz, H.S.; Ebersole, J.L. Correction to Oz, H.S.; Ebersole, Jeffrey L. Application of Prodrugs to Inflammatory Diseases of the Gut. Molecules 2008, 13, 452-474. Molecules 2008, 13, 771. https://doi.org/10.3390/molecules13040771
Oz HS, Ebersole JL. Correction to Oz, H.S.; Ebersole, Jeffrey L. Application of Prodrugs to Inflammatory Diseases of the Gut. Molecules 2008, 13, 452-474. Molecules. 2008; 13(4):771. https://doi.org/10.3390/molecules13040771
Chicago/Turabian StyleOz, Helieh S., and Jeffrey L. Ebersole. 2008. "Correction to Oz, H.S.; Ebersole, Jeffrey L. Application of Prodrugs to Inflammatory Diseases of the Gut. Molecules 2008, 13, 452-474" Molecules 13, no. 4: 771. https://doi.org/10.3390/molecules13040771