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Acylated Flavone Glycosides from the Roots of Saussurea lappa and Their Antifungal Activity

School of Studies in Chemistry, Vikram University, Ujjain 456010, M.P. India
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Molecules 2007, 12(3), 328-344; https://doi.org/10.3390/12030328
Received: 14 November 2006 / Revised: 20 February 2007 / Accepted: 21 February 2007 / Published: 7 March 2007
The isolation of four novel acylated flavonoid glycosides from the roots of Saussurea lappa and their identification using a combination of 1D and 2D NMR and mass spectrometry is described. The in vitro antifungal and antibacterial activities of the isolated compounds and their mixture were tested on nine fungal and four bacterial strains, using the microdilution method. The compounds and mixture showed moderate to high antifungal activity against most of the fungi tested, compared to a miconazole standard, while only one compound and the mixture showed antibacterial activity against all strains tested. View Full-Text
Keywords: Saussurea lappa; acylated flavone glycosides; scutellarein; kaempferol; antifungal acitivity Saussurea lappa; acylated flavone glycosides; scutellarein; kaempferol; antifungal acitivity
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Rao, K.S.; Babu, G.V.; Ramnareddy, Y.V. Acylated Flavone Glycosides from the Roots of Saussurea lappa and Their Antifungal Activity. Molecules 2007, 12, 328-344.

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