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Molecules 2006, 11(9), 726-730;

Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts

Department of Chemistry, Faculty of Natural Sciences, Mathematics and Education, University of Split, N. Tesle 12, 21 000 Split, Croatia
Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10 000 Zagreb, Croatia
Author to whom correspondence should be addressed.
Received: 28 July 2006 / Revised: 30 August 2006 / Accepted: 21 September 2006 / Published: 28 September 2006
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The synthesis of racemic and enantiomerically pure N-p-methylbenzyl-3- and N-p-chlorobenzylbenzamidoquinuclidinium bromides (6-8 and 9-11, respectively) is described. These compounds were prepared from racemic or enantiomerically pure 3-benzamidoquinuclidines 3-5 using the appropriate quaternization reagents: p-methyl- benzyl bromide (1) and p-chlorobenzyl bromide (2). View Full-Text
Keywords: Quinuclidine; N-quaternary salts; quaternization Quinuclidine; N-quaternary salts; quaternization

Figure 1

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Odzak, R.; Tomic, S. Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts. Molecules 2006, 11, 726-730.

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