Urea- Hydrogen Peroxide (UHP) Oxidation of Thiols to the Corresponding Disulfides Promoted by Maleic Anhydride as Mediator
Abstract
:Introduction
Results and Discussion
Solvent | Completion time of reaction [min] | |
---|---|---|
0oC | RT | |
CH2Cl2 | 120a | 120a |
CHCl3 | 140a | 140a |
CH3OH | 10b | 20a |
CH3CN | 30b | 40a |
Run | Thiols | Disulfides | Reaction Time (min.) | Yielda,b (%) | M.P. (oC) Found | M.P. (oC) Literature |
---|---|---|---|---|---|---|
1 | | | 10 | 90 | 144-146 | 142-145 [16] |
2 | | | 10 | 91 | 43-44 | 44-45 [16] |
3 | | | 30 | 90 | 72-73 | 70-71[16] |
4 | | | 20 | 90 | 69-71 | 69-70 [16] |
5 | | | 10 | 95 | 90-92 | 91-93 [16] |
6 | | | 40 | 78 | 55-56 | 55-57 [16] |
7 | | | 60 | 76 | 133-135 | 134-136 [26] |
8 | | | 30 | 65 | 177-179 | 177-180[27] |
9 | | | 60 | 63 | 202-204 | 202-204 [28] |
10 | CH3(CH2)2CH2SH | (CH3(CH2)2CH2S)2 | 18 | 94 | Oil [28] | |
11 | CH3(CH2)6CH2SH | (CH3(CH2)6CH2S)2 | 20 | 93 | Oil [28] | |
12 | n-BuSH | (n-BuS)2 | 20 | 92 | Oil [16] | |
13 | c-C6H11SH | (c-C6H11S)2 | 20 | 94 | Oil [16] |
Conclusions
Experimental
General
Typical procedure for oxidation of 4-methylthiophenol
Acknowledgements
References and Notes
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Karami, B.; Montazerozohori, M.; Habibi, M.H. Urea- Hydrogen Peroxide (UHP) Oxidation of Thiols to the Corresponding Disulfides Promoted by Maleic Anhydride as Mediator. Molecules 2005, 10, 1358-1363. https://doi.org/10.3390/10101385
Karami B, Montazerozohori M, Habibi MH. Urea- Hydrogen Peroxide (UHP) Oxidation of Thiols to the Corresponding Disulfides Promoted by Maleic Anhydride as Mediator. Molecules. 2005; 10(10):1358-1363. https://doi.org/10.3390/10101385
Chicago/Turabian StyleKarami, Bahador, M. Montazerozohori, and M. H. Habibi. 2005. "Urea- Hydrogen Peroxide (UHP) Oxidation of Thiols to the Corresponding Disulfides Promoted by Maleic Anhydride as Mediator" Molecules 10, no. 10: 1358-1363. https://doi.org/10.3390/10101385