Deadline for manuscript submissions: closed (30 November 2009)
Special Issue Editors
Guest Editor Prof. Dr. Liselotte Krenn
Institute of Pharmacognosy, PharmaCenter Vienna, University of Vienna, Althanstr. 14, A-1090 Vienna, Austria
Phone: 00431427755259 Fax: +43 1 4277 9552 Interests: flavonoids; anthraquinones; isolation and structure elucidation; analysis (LC-DAD; LC-MS); in vitro assays (antioxidant properties; acetylcholinesterase inhibition; histonedeacetylase modulation)
Editorial Advisor Prof. Dr. José Alberto Pereira
CIMO/Escola Superior Agrária, Instituto Politécnico de Bragança, Campus Sta Apolónia, Apartado 1 172, 5301-855 Bragança, Portugal
Phone: +351273303277 Fax: +351 273325405 Interests: bioactive phytochemicals; phenolic compounds; antioxidant and antimicrobial activities; effect of agricultural practices on vegetable composition and quality; olives and olive oil chemistry
Editorial Advisor Dr. Paula Andrade
REQUIMTE/LAQV, Laboratory of Pharmacognosy, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, Porto 4050-313, Portugal
Website: http://www.requimte.pt/laqv/people/pandrade Fax: +351-226093390 Interests: metabolite profiling of natural matrices; natural agents for inflammation; neurodegenerative disorders
Special Issue Information
This Special Issue of the International Journal of Molecular Science is dedicated to phenolics and polyphenols. Polyphenols are among the most abundant substances produced in plant kingdom comprising numerous diverse classes of secondary metabolites such as phenolic acids, flavonoids, tannins, coumarins, stilbenes, lignans.
During the recent decades such compounds have gained an enormous interest in research. Their diverse functions in plants, biosynthesis, biological properties etc. are studied in detail. Besides that the health effects of phenolics and polyphenols are investigated intensively. Numerous representatives of these compounds are e.g. assumed to contribute by different modes of action to the prevention of chronic diseases associated with oxidative stress such as cancer or cardiovascular diseases. This has stimulated investigations not only on the activites but also on the concentrations of such compounds in all kinds of food and medicinal plants as well as on their intake, absorption, bioavailability and metabolism. Recommendations to ingest of high amounts for preventional purposes have raised the question of toxicity and led to respective studies.
For the use of extracts rich in polyphenols in herbal medicinal products and food supplements, the development of appropriate analytical methods and optimum formulations are important research fields as well.
Nevertheless, there are still apparent gaps in the knowledge concerning phenolics and polyphenols. Besides many others e.g. the full understanding of their role and function in plants at the molecular level or interactions in the environment need further investigation. Thus, this special issue shall help to fill some of the gaps in all above mentioned fields of research.