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Int. J. Mol. Sci. 2010, 11(2), 622-646; doi:10.3390/ijms11020622
Review

Biological Activities of Polyphenols from Grapes

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Received: 1 December 2009 / Revised: 26 January 2010 / Accepted: 29 January 2010 / Published: 4 February 2010
(This article belongs to the Special Issue Phenolics and Polyphenolics)
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Abstract

The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. Most recent interest has focused on the bioactive phenolic compounds in grape. Anthocyanins, flavanols, flavonols and resveratrol are the most important grape polyphenols because they possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, antiaging and antimicrobial properties. This review summarizes current knowledge on the bioactivities of grape phenolics. The extraction, isolation and identification methods of polyphenols from grape as well as their bioavailability and potential toxicity also are included.
Keywords: grape; polyphenol; bioactivity; antioxidant activity; cardioprotective action; anticancer activity; anti-inflammation activity; antimicrobial effect grape; polyphenol; bioactivity; antioxidant activity; cardioprotective action; anticancer activity; anti-inflammation activity; antimicrobial effect
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Xia, E.-Q.; Deng, G.-F.; Guo, Y.-J.; Li, H.-B. Biological Activities of Polyphenols from Grapes. Int. J. Mol. Sci. 2010, 11, 622-646.

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