Int. J. Mol. Sci. 2010, 11(2), 622-646; doi:10.3390/ijms11020622

Biological Activities of Polyphenols from Grapes

Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China
* Author to whom correspondence should be addressed.
Received: 1 December 2009; in revised form: 26 January 2010 / Accepted: 29 January 2010 / Published: 4 February 2010
(This article belongs to the Special Issue Phenolics and Polyphenolics)
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Abstract: The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. Most recent interest has focused on the bioactive phenolic compounds in grape. Anthocyanins, flavanols, flavonols and resveratrol are the most important grape polyphenols because they possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, antiaging and antimicrobial properties. This review summarizes current knowledge on the bioactivities of grape phenolics. The extraction, isolation and identification methods of polyphenols from grape as well as their bioavailability and potential toxicity also are included.
Keywords: grape; polyphenol; bioactivity; antioxidant activity; cardioprotective action; anticancer activity; anti-inflammation activity; antimicrobial effect

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MDPI and ACS Style

Xia, E.-Q.; Deng, G.-F.; Guo, Y.-J.; Li, H.-B. Biological Activities of Polyphenols from Grapes. Int. J. Mol. Sci. 2010, 11, 622-646.

AMA Style

Xia E-Q, Deng G-F, Guo Y-J, Li H-B. Biological Activities of Polyphenols from Grapes. International Journal of Molecular Sciences. 2010; 11(2):622-646.

Chicago/Turabian Style

Xia, En-Qin; Deng, Gui-Fang; Guo, Ya-Jun; Li, Hua-Bin. 2010. "Biological Activities of Polyphenols from Grapes." Int. J. Mol. Sci. 11, no. 2: 622-646.

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