Special Issue "Natural Anti-Inflammatory Agents"
Deadline for manuscript submissions: closed (30 June 2017)
Dr. Paula Andrade
Dr. Patrícia Valentão
REQUIMTE/LAQV, Laboratory of Pharmacognosy, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, Porto 4050-313, Portugal
Website | E-Mail
Interests: metabolite profiling of natural matrices, marine and terrestrial; evaluation of bioactive agents from natural sources; marine organisms as source of bioactive agents; natural anti-inflammatory agents; neurodegenerative diseases
Inflammation is the organism’s natural response to stimuli that are perceived as harmful, from germs, toxins, environmental pollutants, to injury and stress, among others. This complex process involves immune, vascular and cellular biochemical reactions. At a damaged site, the process starts with the migration of immune cells from blood vessels and release of mediators, followed by recruitment of inflammatory cells and release of various oxidative agents and pro-inflammatory cytokines, arachidonic acid playing a pivotal role. Normal inflammation is self-limiting, but aberrant resolution and prolonged inflammation lead to chronic disorders, as excessive oxidants and inflammatory mediators have deleterious effects, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs, finally leading to systemic disorders. The search of new anti-inflammatory drugs has been a current preoccupation, due to the need of effective drugs, with less adverse reactions than those used nowadays. Concerning this issue, there has been increasing awareness of the potential interest in natural products. This Special Issue is devoted to the exploitation of natural matrices as sources of new anti-inflammatory molecules and their mechanism of action.
Prof. Dr. Paula B. Andrade
Prof. Dr. Patrícia Valentão
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- arachidonic acid
- gene expression
- inflammatory cells
- inflammatory enzymes
- natural products
- transcription factors