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Int. J. Mol. Sci. 2009, 10(11), 4990-5001; doi:10.3390/ijms10114990

Article

Phytochemical Screening and Polyphenolic Antioxidant Activity of Aqueous Crude Leaf Extract of Helichrysum pedunculatum

Olayinka A. Aiyegoro and Anthony I. Okoh*

Applied and Environmental Microbiology Research Group (AEMREG), Department of Biochemistry and Microbiology, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa

* Author to whom correspondence should be addressed.

Received: 10 October 2009; in revised form: 9 November 2009 / Accepted: 12 November 2009 / Published: 13 November 2009

(This article belongs to the Special Issue Phenolics and Polyphenolics)

Download PDF Full-Text [123 KB, uploaded 13 November 2009 15:22 CET]

Abstract: We evaluated the in vitro antioxidant property and phytochemical constituents of the aqueous crude leaf extract of Helichrysum pedunculatum. The scavenging activity on superoxide anions, DPPH, H₂O₂, NO and ABTS; and the reducing power were determined, as well as the flavonoid, proanthocyanidin and phenolic contents of the extract. The extract exhibited scavenging activity towards all radicals tested due to the presence of relatively high total phenol and flavonoids contents. Our findings suggest that H. pedunculatum is endowed with antioxidant phytochemicals and could serve as a base for future drugs.

Keywords: Helichrysum pedunculatum; scavenging; free radicals; antioxidant activity

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