Search Results (41)

Residential mobility within cities reflects the spatio-temporal patterns of individual or household relocation behaviors and serves as an effective tool for interpreting urban socio-spatial differentiation from a micro-level perspective. Newly employed college graduates (NECGs) have become the second-largest migrating population in China. This study selects Guangzhou, a megacity, as the study area and utilizes data from the “Guangzhou New Citizens’ Residential Mobility Survey” conducted in 2023. It applies spatio-temporal systems and the spatio-temporal path method based on time geography to explore the residential mobility trajectories of NECGs in Guangzhou. In addition, the study uses a logistic regression model to explore the influencing factors. The findings indicate that NECGs frequently move across districts, showing no significant patterns of concentration or dispersion. However, residential location choices vary considerably across educational levels and household registration natures (Hukou), and as the duration of residence in Guangzhou increases, the probability of residential mobility among NECGs across all educational levels shows a declining trend. Specifically, marital status (life course attributes), housing prices and medical facilities (housing attributes), and job type (socioeconomic attributes) emerge as critical factors influencing residential mobility. By providing a foundation for urban planning policies, this study aims to support the settlement and well-being of NECGs while promoting high-quality urban development in Guangzhou. Full article

Responding to cost inefficiency in the Indonesian cadastral mapping system, this study aimed to analyze the implementation of integrated mapping activities, namely complete systematic land registration, assessing land value zones, and regional land stewardship balance. This study employed an operational management system, particularly focusing on financial aspects, using data envelopment analysis (DEA), a non-parametric technique for evaluating the relative efficiency of decision-making units. These approaches are rarely explored in cadastral mapping. DEA was used to analyze the efficiency of seven aspects: aerial mapping, office supplies, meetings, consumption, transportation, capital expenses, and socialization. Content analysis was used to identify integration parameters derived from operational management-based integration. Cronbach’s alpha was used for the reliability test. The Way Sulan sub-district of South Lampung Regency in Lampung Province, Indonesia, was selected as the study area due to its complete mapping activities. The findings suggested that applying operational management for integrated cadastral mapping is effective. However, contrary to expectations, efficiency was lower in dense urban areas, where costs tend to be cheaper, while efficiency was higher in agricultural areas, where expenses were much greater. Based on this study, an operational management approach to integrated cadastral mapping is recommended to improve budget efficiency and general standards of land management, especially in areas with complex land use. Full article

Universal Newborn Screening (NBS) programs (for endocrine, immunologic and metabolic disorders) are effective in reducing child morbidity and mortality. Despite available health services, NBS is not carried out for some newborns. The contributing factors for this should be explored. In high-income settings, homebirth generally refers to planned birth at home, attended by skilled health professionals. We aimed to assess trends and characteristics of planned homebirths and the uptake of NBS and infant health practices. A retrospective case-control study including 3246 infants compared planned homebirth (cases) to age-matched hospital birth controls. During 2016–2023, 0.56% of livebirths (1623/290,458) in the Jerusalem District (JD), Israel, were planned homebirths. The rate has increased since 2020 (COVID-19 pandemic), 0.45% in 2016–2019 vs. 0.67% in 2020–2023. Homebirth infants had a higher birthweight, lower firstborn rate and higher socioeconomic rank. The overall NBS uptake in homebirths was significantly lower (73.7% vs. 99.5% in hospital births) and declined over time (81.1% in 2016–2019 vs. 68.7% in 2020–2023). Regarding preventive health practices for homebirth infants, the registration rate to Mother and Child Health Clinics (MCHCs) was lower (47.1% vs. 92.8% in hospital births), and routine immunization rates were decreased (DTaP-IPV-HiB3 90.7% vs. 60.1%). The NBS uptake among homebirth infants was significantly associated with MCHC registration and routine immunizations (RR = 4.15, 95%CI 3.3–5.3). NBS uptake in homebirths is considerably lower and is associated with subsequent patterns of preventive health practices. Notably, the national NBS program data also indicate a trend of increase in non-uptake rates. Barriers to NBS for homebirths should be identified and targeted interventions implemented. The trends in national NBS non-uptake necessitate further follow-up, and evidence from successful outreach programs should be reviewed and translated into guidelines for health organizations. Full article

An important feature of China’s housing market is the coexistence of a high house-price- to-income ratio and high homeownership rates. The purpose of our study is to reveal the root causes of this paradox from a new perspective and theoretical foundation. Based on questionnaire data from Hangzhou and logistic regression models, our research finds that the most important factors driving middle and lower-income groups to buy homes are its unique household registration and school district housing system, underdeveloped housing rental market and inadequate regulatory system, and the wealth appreciation effect caused by the continued rise in housing prices. Furthermore, intergenerational wealth transfers, private lending, and China’s generous home mortgage policies have made homeownership possible for this groups. However, the high house-price-to-income ratio leads to heavy financial pressure on the middle- and low-income groups and is not conducive to sustainable and healthy economic development. To this end, we suggest that the government accelerate the equalization of public services, improve the regulatory system governing the rental housing market, and control the unreasonable rise in housing prices and diversify investment channels for residents. Full article

Agriculture is one of the most culturally and economically important livelihood activities of the Ganges River Delta. In recent years, coastal communities have experienced longer dry seasons and salinity intrusion, which is exacerbated by registration errors in land tenure that have led to increasing encroachment by external interests in the Dacope sub-district of Bangladesh. These challenges threaten to undermine the sustainability of smallholder access to canals that are collectively managed as common-pool resources (CPR). This paper explores how identity and collective action may empower farmers to secure irrigation access in the face of external pressures. Drawing primarily on qualitative data collected through focus group discussions with farmers in Dacope, our findings reveal that identity serves as a powerful force driving collective action and the sustainability of the agricultural community. A shared occupational identity fosters a sense of belonging and collective responsibility among farmers to maintain water flow through construction, annual dredging, and temporary dry-season protections. However, despite a strong commitment to maintaining their irrigation system, challenges remain in farmers’ ability to combat the powerful interests of wealthier members of the community that threaten to undermine the viability of the irrigation commons. Thus, formal support through policy and legislative avenues is also necessary to safeguard common property rights against the threat of privatization and illegal occupation of canals. These findings further underscore the need for more research on how collective identity may strengthen collective action, livelihoods, and sustainability in the absence of strong institutional arrangements that uphold community rights and access to common-pool resources. Full article

Objectives: To determine if early (three months) and late (one year) post-operative continence is improved by performing a novel retropubic vascularised fascial sling (RoboSling) procedure concurrently with robot-assisted radical prostatectomy in men undergoing treatment for localised prostate cancer. To additionally assess surgical outcomes, quality of life and health economic outcomes in patients undergoing the novel RoboSling technique. Methods: This study aims to recruit 120 consecutive patients with clinically localised prostate cancer who have chosen to undergo robot-assisted radical prostatectomy in the Sydney Local Health District, Australia. A prospective assessment of early and late post-operative continence following robot-assisted radical prostatectomy with and without a RoboSling procedure will be performed in a two-group, 1:1, parallel, randomized controlled trial. Four surgeons will take part in the study, all of whom are beyond their learning curve. Patients will be blinded as to whether the RoboSling procedure is performed for them, as will be the research officers collecting the post-operative data on urinary function. Trial Registration: ACTRN12618002058257. Results: The trial is currently underway. Conclusions: The RoboSling technique is unique in that the sling is vascularised and has a broad surface area compared to previously described slings in the literature. If a clinically significant improvement in post-operative continence is established with the RoboSling, then, we can in turn expect improvements in quality of life for men undergoing this technique with radical prostatectomy. Full article

The aim of the present study consists of the evaluation of the biodistribution of a novel ⁶⁸Ga-labeled radiopharmaceutical, [⁶⁸Ga]Ga-NODAGA-Z360, injected into Balb/c nude mice through histopathological analysis on bioptic samples and radiomics analysis of positron emission tomography/computed tomography (PET/CT) images. The ⁶⁸Ga-labeled radiopharmaceutical was designed to specifically bind to the cholecystokinin receptor (CCK2R). This receptor, naturally present in healthy tissues such as the stomach, is a biomarker for numerous tumors when overexpressed. In this experiment, Balb/c nude mice were xenografted with a human epidermoid carcinoma A431 cell line (A431 WT) and overexpressing CCK2R (A431 CCK2R+), while controls received a wild-type cell line. PET images were processed, segmented after atlas-based co-registration and, consequently, 112 radiomics features were extracted for each investigated organ / tissue. To confirm the histopathology at the tissue level and correlate it with the degree of PET uptake, the studies were supported by digital pathology. As a result of the analyses, the differences in radiomics features in different body districts confirmed the correct targeting of the radiopharmaceutical. In preclinical imaging, the methodology confirms the importance of a decision-support system based on artificial intelligence algorithms for the assessment of radiopharmaceutical biodistribution. Full article

This article examines the importance of landholdings in explaining income inequality among family farms in four districts in Georgia following the land reform of the 1990s. Income inequality is decomposed by sources of income and by determinants of income. The results indicate that farm income is a disequalizing source of income among family farms in these districts. In addition, a uniform increase in landholding is expected to reduce income inequality. Combining the two results, we conclude that the impact of land reform on farm household income inequality depends on the resulting distribution of landholdings. It can reduce inequality if land is distributed relatively equally, but inequality can increase if the wealthier farmers are able to gain control of more (and perhaps better) land resources. A possible implication of this result is that for land reform to be equalizing, distributing land to smallholders should be accompanied by additional policies and regulations supporting small farmers, such as land titling and registration, support for cooperation, and access to credit and other market services. Full article

Records of asylums, schools, and benevolent organisations that intervened in the lives of disabled children in Scotland during the long nineteenth century have survived to varying degrees in public and institutional archives. This might suggest the existence of detailed primary source material that stands in contrast to the sparse data about those disabled children who ‘escaped’ the attention of organisations that aimed to support and direct their lives. However, the records of these formal organisations are inconsistent in what they reveal about the lives of the children under their patronage. This article explores the challenges presented by the records of three organisations, namely, the Scottish National Institution for the Education of Imbecile Children in Larbert, Edinburgh’s Gayfield Square blind school, and East Park Home for Aiding Infirm Children in the Maryhill district of Glasgow. Among the deficiencies of surviving institutional records are the frequent paucity of insights into the lives of their young residents. This article will consider how some of their life journeys can nonetheless be researched by marshalling data from the likes of mandatory registration records and decennial census enumerators’ books. In addition to benefits afforded to genealogists, such records provide historians with materials from which disabled lives can be reconstructed and analysed. Full article

The sustainable development goals (SDGs) provide an integrated framework of targets and indicators, including the elimination of stunting, to support better development planning. Indonesia faces a significant challenge as it ranks fourth globally in terms of stunting prevalence, exacerbated by disparities across regions, gender, and socioeconomic status, further compounded by the ongoing COVID-19 pandemic. Given the interlinked nature of SDGs, this study provides empirical support for the prioritization of SDG indicators, primarily in the context of stunting elimination at the district level in Indonesia. This study employed a combination of economic complexity and network theory, utilizing data from a comprehensive set of 54 indicators spanning 28 targets within 13 SDG goals in 514 districts. The analysis is based on network metrics, including revealed comparative advantage (RCA), proximity, centrality, and density to establish the SDG interlinkage network and identify key priority indicators. The findings highlight the importance of prioritizing indicators such as civil registration, health facilities and services, access to basic facilities and housing, and access to ICT in efforts to reduce stunting, particularly among disadvantaged households. Given the unique resources and capacities of each region, our analysis offers district-specific prioritization strategies for stunting elimination. Full article

The pandemic situation of COVID-19, which affected almost the entire civilized world with its consequences, offered a unique opportunity for analysis of geographical space. In a relatively short period of time, the COVID-19 pandemic became a truly global event with consequences affecting all areas of life. Circumstances with COVID-19, which affected the territory of Slovakia and its regions, represent a sufficient premise for analysis three years after the registration of the first case in Slovakia. The study presents the results of a detailed spatiotemporal analysis of the course of registered cases of COVID-19 in six periods in Slovakia. The aim of the paper was to analyze the development of the number of people infected with the disease COVID-19 in Slovakia. At the level of the districts of Slovakia, using spatial autocorrelation, we identified spatial differences in the disease of COVID-19. Moran’s global autocorrelation index and Moran’s local index were used in the synthesis of knowledge. Spatial analysis of data on the number of infected in the form of spatial autocorrelation analysis was used as a practical sustainable approach to localizing statistically significant areas with high and low positivity. This manifested itself in the monitored area mainly in the form of positive spatial autocorrelation. The selection of data and methods used in this study together with the achieved and presented results can serve as a suitable tool to support decisions in further measures for the future. Full article

Throughout history, tools for engineering in the building industry have evolved. Due to the arrival of Industry 4.0, Computer-Aided Design (CAD) and Building Information Modeling (BIM) software have replaced the usage of pens, pencils, and paper in the design process. This paper describes the work required to design a large-scale immersive visit of a district under construction in a suburban area of Greater Paris, France. As part of this real estate project, called LaVallée, we have access to its city information model: all the BIMs of the works to be carried out including roads, terrain, street furniture, fountains, and landscaping. This paper describes all the technical operations necessary for the design of an immersive 3D model with a high level of detail of the neighborhood with its surroundings. The objective of this technical report was to provide practitioners with feedback on such an achievement based on industrial-level data. The development of the city model begins with the registration of all the BIMs from different firms in a common Geographic Information System: this gives the opportunity to confront the operational requirement of a construction phase and the actual current practice of architecture firms. A first prototype was developed using the archviz tool TwinMotion. In order to increase the realism of the model, we describe the creation of a pipeline in Unreal Engine with the automated tasks of material and mesh replacement and the lighting and landscape configuration. The main contribution of this work is to give relevant experience on building such a large-scale model, with the Python script when possible, as well as the necessary manual steps. It is a valuable contribution to the making of large-scale immersive visits with a high level of detail and their requirements. Full article

Historical death registration was conducted primarily to assess the presence of plague. The Liber Mortuorum of Milan was one of Europe’s first registers with many socio-demographical details. In this work, we consider 1480 to make spatial and temporal analyses of the event of death to find possible explanations about the events’ distribution and the events’ trend over time. The spatial analyses involved Moran’s I, the LISA, and the heatmaps; the temporal analysis applied the Durbin-Watson test. All the analyses were conducted separately on all subjects (1813), children (765), and adults (1046). Contrade (districts) were considered for spatial analysis. Moran’s I and the Durbin Watson test were significant on all subjects and children’s analyses, and the LISA showed the same results for those groups. Children may significantly impact the distribution of death and the trend over time. At least half of the children were 0 years old, and survival in the very first childhood period was closely linked to the family, so that it could be a proxy of the conditions of an area. Full article

Introduction: Pre-diabetes is an intermediate, asymptomatic state between normoglycaemia and the onset of type 2 diabetes mellitus (T2D). Recent reports indicate that there are sub-clinical changes observed in red blood cells during pre-diabetes. This systematic review protocol will provide an outline of all procedures in the synthesis of the available data on the changes in red blood cell indices. Methods and Analysis: This protocol was prepared by adhering to the PRISMA 2015 guidelines for reporting protocols. Published clinical studies that involve observation, whether it is cross-sectional, comparative cross-sectional, case-control or cohort study designs that involve normal/non-diabetic and pre-diabetes reports were used. Additionally, this was accomplished by using clinical MeSH headings to search on MEDLINE, COCHRANE library and African Journal Online. Three reviewers (NCM, AMS & AK) screened all the results for eligibility criteria. Then, Downs and Black checklist was used to check the risk of bias. Review Manager v5.4 Forrest plot was used for meta-analysis and sensitivity analysis. Strength of evidence was then assessed using the Grading of Recommendations Assessment, Development, and Evaluation approach (GRADE). Results and Conclusion: This protocol will give direction on the exploration of articles that report on changes in red blood cell indices in the pre-diabetic state. The results obtained from this protocol will further give direction on the research to be done at in the eThekwini district of South Africa. Ethics and Dissemination: The data that will be analyzed will be data that has already been published thus there will be no data collection from subjects. Therefore, no ethical clearance is required. Registration Details: This protocol has been registered with the International Prospective Registry of Systematic Reviews (PROSPERO) registration number “CRD42020189080” dated 05-07-2020. Full article

Introduction: Dental caries in the adult population that require preventive and therapeutic treatment are generally neglected in rural communities. The determination of the effectiveness of the application of 38% silver diamine fluoride (SDF) in arresting caries lesions when combined with atraumatic restorative treatment (ART) is very important, as it serves as a preventive and restorative procedure to regain the function of the permanent dentition. The assessment of optimal SDF application with ART, in comparison with ART alone, in managing cavitated carious lesions in a pragmatic setting, is the need of the hour to recommend optimal dental care, especially in rural settings which have minimal access to comprehensive dental care. Methods and Analysis: The clinical trial will enrol 220 adults (18–65 years) with cavitated carious lesions attending the Amrita School of Dentistry in the Ernakulam district, India. This study is a randomized, controlled trial with a 1:1 allocation ratio in two parallel groups. Study arm 1 will receive 38% SDF application and ART, and study arm 2 will receive ART only. A digital radiograph will be taken immediately after restoration (baseline) as well as at the end of the 6th month for evaluation of caries arrest. The assessment of the survival of the restoration will be done on the 7th day, 30th day, and at the end of the 6th month. The final analysis would include both the tooth and person levels. Ethics and Dissemination: This trial adheres to the principles of the Declaration of Helsinki and the guidelines of the Indian Council of Medical Research (ICMR). This study protocol has been approved by the Institutional Review Board. This trial has been registered prospectively with the Clinical Trial Registry of India (Registration No: CTRI/2021/12/038816). Full article