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  • Article
  • Open Access
53 Citations
10,352 Views
21 Pages

The Effects of Probiotic Supplementation on the Incidence of Diarrhea in Cancer Patients Receiving Radiation Therapy: A Systematic Review with Meta-Analysis and Trial Sequential Analysis of Randomized Controlled Trials

  • Navin Kumar Devaraj,
  • Subapriya Suppiah,
  • Sajesh K. Veettil,
  • Siew Mooi Ching and ,
  • Kai Wei Lee,
  • Rohit Kunnath Menon,
  • Man Jun Soo,
  • Inas Deuraseh,
  • Fan Kee Hoo and
  • Dhashani Sivaratnam
  • + 5 authors+ 0 author

27 November 2019

The protective effects of probiotic supplementation against radiation-induced diarrhea (RID) have been reported in previous systematic reviews; however so far, only non-conclusive results have been obtained. The objective of this study was to systema...

  • Review
  • Open Access
28 Citations
9,714 Views
29 Pages

Food Supplements to Mitigate Detrimental Effects of Pelvic Radiotherapy

  • Charlotte Segers,
  • Mieke Verslegers,
  • Sarah Baatout,
  • Natalie Leys and ,
  • Sarah Lebeer and
  • Felice Mastroleo
  • + 1 author+ 0 author

Pelvic radiotherapy has been frequently reported to cause acute and late onset gastrointestinal (GI) toxicities associated with significant morbidity and mortality. Although the underlying mechanisms of pelvic radiation-induced GI toxicity are poorly...

(This article belongs to the Section Gut Microbiota)
  • Article
  • Open Access
9 Citations
11,823 Views
12 Pages

18 April 2008

Curative radiation therapy of pelvic malignancies, frequently results in doselimitingtoxicities such as serous, mucoid, or more rarely, bloody diarrhea. Several studieshave evaluated the cytoprotective effects of amifostine in preventing rectal mucos...

(This article belongs to the Special Issue Prodrugs)
  • Article
  • Open Access
7 Citations
8,511 Views
12 Pages

Clinical Features and Management of Acute and Chronic Radiation-Induced Colitis and Proctopathy

  • Hamzah Abu-Sbeih,
  • Tenglong Tang,
  • Faisal S. Ali,
  • Weijie Ma and ,
  • Malek Shatila,
  • Wenyi Luo,
  • Dongfeng Tan,
  • Chad Tang,
  • David M. Richards and
  • Yinghong Wang
  • + 7 authors+ 2 authors

12 June 2023

Background: RICAP is a recognized adverse effect of radiation therapy (RT) that can adversely affect cancer patients’ quality of life. Data on the clinical characteristics and outcomes of RICAP are scarce. We aimed to analyze the clinical and e...

(This article belongs to the Section Cancer Therapy)
  • Article
  • Open Access
2 Citations
3,239 Views
9 Pages

Probiotic Bacteria Cannot Mitigate the Adverse Effects of Radioactive Iodine-131 Treatment

  • Seyed Mohammad Javad Mortazavi,
  • Saba Nowroozi,
  • Masoud Haghani,
  • Zinat Zarrini-Monfared and ,
  • Farshid Gheisari and
  • Lembit Sihver
  • + 1 author+ 0 author

25 January 2023

Thyroid carcinoma is the most common cancer of the endocrine system, accounting for 12% of all cancer cases in adolescents in the United States. Radioiodine therapy plays a key role in differentiated thyroid cancer (DTC) treatment. This double-blind,...

  • Review
  • Open Access
37 Citations
6,001 Views
16 Pages

The Impact of Probiotics on Intestinal Mucositis during Chemotherapy for Colorectal Cancer: A Comprehensive Review of Animal Studies

  • Povilas Miknevicius,
  • Ruta Zulpaite,
  • Bettina Leber,
  • Kestutis Strupas and ,
  • Philipp Stiegler and
  • Peter Schemmer
  • + 1 author+ 0 author

28 August 2021

Colorectal cancer (CRC) is the second most commonly diagnosed cancer in females (incidence 16.4/10,000) and the third in males (incidence 23.4/10,000) worldwide. Surgery, chemotherapy (CTx), radiation therapy (RTx), or a combined treatment of those a...

(This article belongs to the Special Issue Recent Advances and Future Perspective in Microbiota and Probiotics)
  • Article
  • Open Access
12 Citations
4,823 Views
19 Pages

In Vitro Anti-Photoaging and Skin Protective Effects of Licania macrocarpa Cuatrec Methanol Extract

  • Kon Kuk Shin,
  • Sang Hee Park,
  • Hye Yeon Lim,
  • Laura Rojas Lorza and ,
  • Nurinanda Prisky Qomaladewia,
  • Long You,
  • Nur Aziz,
  • Soo Ah Kim,
  • Jong Sub Lee and
  • Jae Youl Cho
  • + 10 authors+ 5 authors

23 May 2022

The Licania genus has been used in the treatment of dysentery, diabetes, inflammation, and diarrhea in South America. Of these plants, the strong anti-inflammatory activity of Licania macrocarpa Cuatrec (Chrysobalanaceae) has been reported previously...

(This article belongs to the Special Issue Antioxidant Capacity of Plant Extracts)
  • Review
  • Open Access
86 Citations
21,743 Views
14 Pages

Selenium in Oncology: From Chemistry to Clinics

  • Oliver Micke,
  • Lutz Schomburg,
  • Jens Buentzel,
  • Klaus Kisters and
  • Ralph Muecke

12 October 2009

The essential trace element selenium, which is a crucial cofactor in the most important endogenous antioxidative systems of the human body, is attracting more and more the attention of both laypersons and expert groups. The interest of oncologists ma...

(This article belongs to the Special Issue Selenium and Tellurium Chemistry)
  • Article
  • Open Access
5 Citations
3,596 Views
17 Pages

Pharmacodynamic Evaluation of Phage Therapy in Ameliorating ETEC-Induced Diarrhea in Mice Models

  • Yangjing Xiong,
  • Lu Xia,
  • Yumin Zhang,
  • Guoqing Zhao and ,
  • Shidan Zhang,
  • Jingjiao Ma,
  • Yuqiang Cheng,
  • Hengan Wang,
  • Jianhe Sun and
  • Zhaofei Wang
  • + 6 authors+ 1 author

Enterotoxigenic Escherichia coli (ETEC) is a major pathogen causing diarrhea in humans and animals, with increasing antimicrobial resistance posing a growing challenge in recent years. Lytic bacteriophages (phages) offer a targeted and environmentall...

(This article belongs to the Section Microbial Biotechnology)
  • Review
  • Open Access
37 Citations
6,888 Views
8 Pages

Selenium in Radiation Oncology—15 Years of Experiences in Germany

  • Ralph Muecke,
  • Oliver Micke,
  • Lutz Schomburg,
  • Jens Buentzel and ,
  • Klaus Kisters,
  • Irenaeus A. Adamietz and
  • On behalf of AKTE
  • + 2 authors+ 0 author

13 April 2018

Introduction: Se measurement and supplementation in radiation oncology is a controversial issue. The German Working Group Trace Elements and Electrolytes in Oncology (AKTE) has conducted a number of studies on this issue, which are summarized in this...