Search Results (22)

Thoroughbred race performance is influenced by genetics, training, recovery, and management, but decisions about race readiness are often subjective and lack validated physiological markers. This study evaluated thiol-oxidised albumin, a blood-based indicator of oxidative stress, as a potential biomarker of pre-race fitness in Australian Thoroughbreds. Seventy-five clinically healthy racehorses from seven stables were monitored across 216 competitive events (150 races, 66 trials). Blood samples were collected from the jugular at baseline, 48 h pre-race, and for each day up to 8 days post-race to examine levels of thiol-oxidised using the OxiDx test. At baseline, thiol-oxidised albumin levels were stable, but 24% of horses exhibited oxidative stress before racing, rising to 53% after three consecutive races. Thiol-oxidised albumin levels also remained increased for at least 8 days post-race. Statistical analyses were conducted in GraphPad Prism 10.6 using paired t-tests or repeated-measures one-way ANOVA with Dunnett’s post hoc test, alongside a generalised estimating equation model to assess associations with ordinal variables; significance was set at p < 0.05. Reference change values were calculated to determine thresholds for biologically meaningful changes in thiol-oxidised albumin levels. Increased pre-race oxidative stress was significantly associated with poorer finishing positions and lower trainer-perceived performance but was unrelated to horse age or sex. Horses without oxidative stress were more likely to finish in the top three. These findings demonstrate that oxidative stress prior to racing is common and adversely affects performance. Thiol-oxidised albumin represents a promising objective biomarker to guide training and racing strategies, with implications for both performance and equine welfare. Full article

The off-the-track Thoroughbred’s (OTTTB’s) suitability for equestrian retraining and rehoming should always be subject to behavioral considerations. Certain attributes may be advantageous to a horse’s racing performance but unfavorable to their prospects off the track. It is important to gain a non-biased understanding of how Thoroughbreds (TBs) in equestrian disciplines compare with other horses behaviorally, to minimize risks of poor welfare and safety outcomes. The current study used owner-reported information (n = 1633) from the Equine Behavior Assessment and Research Questionnaire (E-BARQ) global database to compare the behaviors of OTTTBs with those of other ridden horses. Boldness, compliance, rideability, trainability, and responsiveness to acceleration and deceleration signals were evaluated in the context of 27 E-BARQ items, as determined by exploratory factor analysis (EFA). In this study, OTTTBs demonstrated more boldness (t = 3.793; p < 0.001) and lower compliance and responsiveness to deceleration signals (t = 3.448; p < 0.001) than non-OTTTBs. Trainability, rideability, and responsiveness to acceleration signals did not differ significantly between OTTTBs and non-OTTTBs. These findings provide direction for future research into causal factors and improvement opportunities regarding the training and management of Thoroughbreds, on- and off-the-track. Full article

Horseracing has identified several factors influencing staff wellbeing; however, the relationship between injury, anxiety, and depression is yet to be established. This study investigated anxiety and depression scores and their association to pain management, coping, and help-seeking behaviour in injured British horseracing staff. An online retrospective survey was completed by 175 participants, identifying injury prevalence, coping strategies, occupational risk factors, and Hospital Anxiety and Depression Scale (HADS) scores. Analysis identified 65.14% (n = 114) of staff reported anxiety scores above the threshold (≥8) and 59.52% (n = 104) of staff reported depression scores ≥8. Median anxiety and depression scores were higher for staff who viewed their employer as unhelpful (anxiety p = 0.001; depression p = 0.020). Heightened anxiety and depression were associated with an increased likelihood to use pain medication to manage at work, including non-steroidal anti-inflammatory drugs (NSAID’s), alcohol, nicotine, and prescription drugs (p < 0.05). Implications for staff wellbeing is evident; anxiety and depression risks are high following injury, which may influence help-seeking behaviour, perceived job security, and coping mechanisms. This paper suggests it is vital to continue to investigate poor mental health and injury in racing staff and the implications for equine welfare. Full article

The 2023 Grand National steeplechase race was delayed when protesters from the animal rights group, ‘Animal Rising’, gained access to the course just prior to the race. The international media spotlight was focused on what is already a high-profile event and the social licence of both this race and racing in general was scrutinised. Both at the time and for several days afterwards, the general public was exposed to two different narratives from pro- and anti-racing communities. This paper discusses these perspectives and the potential impact on the general public’s relationship with racing. Whilst well-meaning and aiming to promote racing, much of the racing industry’s commentary inadvertently risked damaging its reputation due to a poor understanding of social licence principles. We explore the reasons for these two groups’ alternative perspectives on welfare and suggest considerations for change. Ultimately, if ‘the people’s race’ is to maintain its social licence, the racing community needs to both understand and embrace the concept. Welcoming independent opinions, engaging with different viewpoints, accepting that change is inevitable and, most importantly, being proactive in making changes to prioritise equine welfare will all help racing to move towards greater public acceptance. Full article

(1) Background: Since antiquity, it is considered that sounds influence human emotional states and health. Acoustic enrichment has also been proposed for domestic animals. However, in both humans and animals, effects vary according to the type of sound. Human studies suggest that frequencies, more than melodies, play a key role. Low and high frequencies, music tuning frequency and even EEG slow waves used for ‘neurofeedback’ produce effects. (2) Methods: We tested the possible impact of such pure frequencies on racehorses’ behavior and physiology. A commercial non-audible acoustic stimulus, composed of an array of the above-mentioned frequencies, was broadcasted twice daily and for three weeks to 12 thoroughbred horses in their home stall. (3) Results: The results show a decrease in stereotypic behaviors and other indicators such as yawning or vacuum chewing, an increase in the time spent in recumbent resting and foraging, and better hematological measures during and after the playback phase for 4 of the 10 physiological parameters measured. (4) Conclusions: These results open new lines of research on possible ways of alleviating the stress related to housing and training conditions in racehorses and of improving physical recovery. Full article

Fatigue-related subchondral bone injuries of the third metacarpal/metatarsal (McIII/MtIII) bones are common causes of wastage, and they are welfare concerns in racehorses. A better understanding of bone health and strength would improve animal welfare and be of benefit for the racing industry. The porosity index (PI) is an indirect measure of osseous pore size and number in bones, and it is therefore an interesting indicator of bone strength. MRI of compact bone using traditional methods, even with short echo times, fail to generate enough signal to assess bone architecture as water protons are tightly bound. Ultra-short echo time (UTE) sequences aim to increase the amount of signal detected in equine McIII/MtIII condyles. Cadaver specimens were imaged using a novel dual-echo UTE MRI technique, and PI was calculated and validated against quantitative CT-derived bone mineral density (BMD) measures. BMD and PI are inversely correlated in equine distal Mc/MtIII bone, with a weak mean r value of −0.29. There is a statistically significant difference in r values between the forelimbs and hindlimbs. Further work is needed to assess how correlation patterns behave in different areas of bone and to evaluate PI in horses with and without clinically relevant stress injuries. Full article

Hair follicles (HF) represent a useful tissue for monitoring the circadian clock in mammals. Irregular light exposure causes circadian disruption and represents a welfare concern for stabled horses. We aimed to evaluate the impact of two stable lighting regimes on circadian clock gene rhythmicity in HF from racehorses. Two groups of five Thoroughbred racehorses in training at a commercial racehorse yard were exposed to standard incandescent light or a customized LED lighting system. The control group received light from incandescent bulbs used according to standard yard practice. The treatment group received timed, blue-enriched white LED light by day and dim red LED light at night. On weeks 0 and 20, mane hairs were collected at 4 h intervals for 24 h. Samples were stored in RNAlater at −20 °C. RNA was isolated and samples interrogated by quantitative PCR for the core clock genes: ARNTL, CRY1, PER1, PER2, NR1D2, and the clock-controlled gene DBP. Cosinor analyses revealed 24 h rhythmicity for NR1D2 and PER2 and approached significance for CRY1 (p = 0.013, p = 0.013, and p = 0.051, respectively) in week 20 in the treatment group only. No rhythmicity was detected in week 0 or in week 20 in the HF of control horses. Results suggest that lighting practices in racehorse stables may be improved to better stimulate optimum functioning of the circadian system. Full article

The impact of recommended withholding periods (RWPs) for omeprazole on the recurrence of Equine Gastric Ulcer Syndrome (EGUS) is unknown. The study was designed to compare the effect of two RWPs on EGUS recurrence post-omeprazole treatment and to determine if a nutraceutical supplement would reduce EGUS recurrence when administrated during an RWP. The study was a blinded, randomized clinical trial. Part 1: Horses were allocated to an RWP0 or RWP2 and crossed over after 4-weeks. Horses received oral omeprazole once daily, except during the RWPs at the end of the treatment periods. Part 2: Horses received omeprazole for 21 days prior to an RWP2 during which they received a nutraceutical supplement. Gastroscopy was performed on Day 0 and pre- and post- RWP. Part 1: More horses were affected by Equine Squamous Gastric Disease (ESGD) after the ‘2-clear-days’ RWP than the ‘not on race-day’ RWP (p = 0.012). The prevalence of ESGD post-RWP for ‘2-clear-days’ did not differ from day 0 (p = 0.478). Part 2: The prevalence of ESGD post-RWP was lower than on Day 0 (p = 0.046). A difference in recurrence of ESGD was present between the two common RWPs. The implications of this on the welfare of Thoroughbred racehorses warrant further discussion. Full article

Racehorse welfare is a prominent, public issue which affects nearly every aspect of the racing industry. Thoroughbred care after race career completion has garnered increasing attention from the equine industry, general public, and animal welfare groups alike. As the average racehorse’s career lasts just 4.5 years, owner demand for thoroughbreds is essential for post-race careers and acceptable welfare standards. This study utilized data from and hedonic pricing models to analyze buyer demand for thoroughbreds sold in online auctions held from 2012 to 2020. The results indicate buyer preferences for age (p < 0.01), sex (p < 0.05), and organization registration (p < 0.05), with bid price premiums for age and registration status (USEF, USEA, USHJA, etc.) and price discounts for mares compared to geldings and horses listed for non-competition careers (trail, p < 0.01). The results of this study confirm and quantify the value potential buyers place on thoroughbreds offered for sale in sport disciplines. The findings may help non-profit organizations charged with rehoming off the track thoroughbreds and reduce the number of unwanted thoroughbreds by illustrating the desired traits and skills within the equine market, thus improving welfare optics overall. Full article

The Thoroughbred racing industry faces new and competing pressures to operate within a modern, changing society. Three major moderators drive the focus and productivity of the industry worldwide: economic sustainability, horse biology and social licence to operate. This review proposes that despite the apparent homogeneity in the structure of racing across jurisdictions due to international regulation of the sport, there are significant differences within each jurisdiction in each of the three moderators. This creates challenges for the comparison of injury risk factors for racehorses within the industry across different jurisdictions. Comparison of the relative distribution of racing and gambling metrics internationally indicates that the Asian jurisdictions have a high focus on gambling efficiency and high economic return of the product, with a high number of starts per horse and the highest relative betting turnover. In contrast, the racing metrics from the USA have proportionally low racing stakes and fewer horses per race. These differences provide insight into the sociology of horse ownership, with a shift from the long-term return on investment held by most jurisdictions to a short-term transitional view and immediate return on investment in others. Wastage studies identify varying risks influenced by the predominant racing culture, training methods, production focus and environment within individual jurisdictions. Increasing societal pressure to maintain high racehorse welfare and reduce the negative impact of gambling poses fluctuating risks to each jurisdiction’s social licence to operate. Based on the data presented within this review, the authors propose that the use of a bioeconomic model would permit consideration of all three moderators on industry practice and optimisation of the jurisdiction-specific production cycle with a horse-centric welfare perspective. Full article

We validated a Thoroughbred racehorse welfare index, developed initially from expert opinion, by relating it to horse behaviour recorded in a range of training stables and surveying trainers to investigate the environment and management systems for Thoroughbred racehorses. Relationships between the index scores and horse behaviour were observed. Then, an Australia-wide survey of racing industry stakeholders was conducted to identify which parameters are important for welfare in a training stable. Trainers performed well on horsemanship and health/disease aspects. Provisions for ventilation, transportation and nutrition were also scored at high levels. However, provisions for weaning, wastage, assisting horses in coping with heat stress, stabling and the education of racehorses were not as well covered, indicating a need for improvement in these welfare issues. We concluded that our Thoroughbred Racehorse welfare index is able to discriminate between trainers offering differing levels of welfare for the major issues in racehorse training stables. Full article

In the 2019/20 Thoroughbred racing season, the paper-based reporting process of stipendiary steward reports was upgraded to an online system (‘Infohorse database’) to allow for the rapid entry of precise event and injury data. The objectives of this study were to describe the incident and non-incident examinations during the 2019/20, 2020/21, and 2021/22 Thoroughbred flat racing seasons in New Zealand and describe the primary injury and reporting outcomes. The introduction of the online system was associated with fewer miscoding events with horse identification (0.1%). An improvement in the definition and prompts in reporting within the online system compared with the previous paper-based system resulted in a greater frequency of non-incident examinations being undertaken. The increased frequency of reporting the clinical outcome, ‘no observable abnormalities detected’ (NOAD), demonstrates the role of stipendiary stewards to carry out routine screening. The frequency of most clinical findings, such as musculoskeletal fractures (0.5 per 1000 starts, 95% CI = 0.3–0.6), remained similar compared to previously reported data using the paper-based system. The online system provided a more structured dataset compared with the paper-based system, making it a useful tool for the monitoring of incidents, injuries, and potential risk factors within Thoroughbred racing in New Zealand. Therefore, evidence-based changes to the management and structure of racing can be undertaken to ensure the industry meets its duty of care for racehorse and jockey welfare. Full article

A catastrophic fracture of the radial carpal bone experienced by a racehorse during a Palio race was analyzed. Computational modelling of the carpal joint at the point of failure informed by live data was generated using a multibody code for dynamics simulation. The circuit design in a turn, the speed of the animal and the surface characteristics were considered in the model. A macroscopic examination of the cartilage, micro-CT and histology were performed on the radio-carpal joint of the limb that sustained the fracture. The model predicted the points of contact forces generated at the level of the radio-carpal joint where the fracture occurred. Articular surfaces of the distal radius, together with the proximal articular surface of small carpal bones, exhibited diffuse wear lines, erosions of the articular cartilage and subchondral bone exposure. Even though the data in this study originated from a single fracture and further work will be required to validate this approach, this study highlights the potential correlation between elevated impact forces generated at the level of contact surfaces of the carpal joint during a turn and cartilage breakdown in the absence of pre-existing pathology. Computer modelling resulted in a useful tool to inversely calculate internal forces generated during specific conditions that cannot be reproduced in-vivo because of ethical concerns. Full article

Identifying key welfare issues for thoroughbred racehorses could lead to an improvement in standards. A lack of scientific information on the relative importance of key issues was addressed by soliciting the views of, first, welfare experts in the industry and, second, a broader group of stakeholders, who selected the best welfare options by adaptive conjoint analysis. The experts represented racehorse breeders, veterinarians, trainers, owners, government officials, salespeople, farriers, transporters, and horse re-trainers for post-racing activities. In a focus group meeting, the experts identified fourteen key welfare issues, each with two to four levels that related to common husbandry practices. Then, in an internet survey, 224 stakeholders ranked the issues using adaptive conjoint analysis, in declining importance, as: horsemanship > health and disease > education of the horse > track design and surface > ventilation > stabling > weaning > transport > nutrition > wastage > heat and humidity > whips > environment > gear. Relatively uniform responses to the survey by the different stakeholder groups suggested that there was a common view on what had the biggest impact on welfare. An exception was a greater rating given by women than men to the importance of correct horse nutrition. The rating of importance for welfare of different levels of provision of each issue mostly conformed to the scientific evidence, with the exception of weaning. This understanding of the importance of welfare issues for thoroughbred racehorses could be used to target interventions to the most serious problems. Full article

Despite many recent advances in imaging and epidemiological data analysis, musculoskeletal injuries continue to be a welfare issue in racehorses. Peptide biomarker studies have failed to consistently predict bone injury. Molecular profiling studies provide an opportunity to study equine musculoskeletal disease. A systematic review of the literature was performed using preferred reporting items for systematic reviews and meta-analyses protocols (PRISMA-P) guidelines to assess the use of miRNA profiling studies in equine and human musculoskeletal injuries. Data were extracted from 40 papers between 2008 and 2020. Three miRNA studies profiling equine musculoskeletal disease were identified, none of which related to equine stress fractures. Eleven papers studied miRNA profiles in osteoporotic human patients with fractures, but differentially expressed miRNAs were not consistent between studies. MicroRNA target prediction programmes also produced conflicting results between studies. Exercise affected miRNA profiles in both horse and human studies (e.g., miR-21 was upregulated by endurance exercise and miR-125b was downregulated by exercise). MicroRNA profiling studies in horses continue to emerge, but as yet, no miRNA profile can reliably predict the occurrence of fractures. It is very important that future studies are well designed to mitigate the effects of variation in sample size, exercise and normalisation methods. Full article