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Keywords = pyocyanase

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18 pages, 634 KiB  
Review
Colour Me Blue: The History and the Biotechnological Potential of Pyocyanin
by Thiago Gonçalves and Ulrich Vasconcelos
Molecules 2021, 26(4), 927; https://doi.org/10.3390/molecules26040927 - 10 Feb 2021
Cited by 68 | Viewed by 9561
Abstract
Pyocyanin was the first natural phenazine described. The molecule is synthesized by about 95% of the strains of Pseudomonas aeruginosa. From discovery up to now, pyocyanin has been characterised by a very rich and avant-garde history, which includes its use in antimicrobial therapy, [...] Read more.
Pyocyanin was the first natural phenazine described. The molecule is synthesized by about 95% of the strains of Pseudomonas aeruginosa. From discovery up to now, pyocyanin has been characterised by a very rich and avant-garde history, which includes its use in antimicrobial therapy, even before the discovery of penicillin opened the era of antibiotic therapy, as well as its use in electric current generation. Exhibiting an exuberant blue colour and being easy to obtain, this pigment is the subject of the present review, aiming to narrate its history as well as to unveil its mechanisms and suggest new horizons for applications in different areas of engineering, biology and biotechnology. Full article
(This article belongs to the Collection Bioactive Compounds)
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