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Keywords = punaglandins

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23 pages, 2265 KiB  
Review
Prostaglandins in Marine Organisms: A Review
by Federica Di Costanzo, Valeria Di Dato, Adrianna Ianora and Giovanna Romano
Mar. Drugs 2019, 17(7), 428; https://doi.org/10.3390/md17070428 - 23 Jul 2019
Cited by 70 | Viewed by 11343
Abstract
Prostaglandins (PGs) are lipid mediators belonging to the eicosanoid family. PGs were first discovered in mammals where they are key players in a great variety of physiological and pathological processes, for instance muscle and blood vessel tone regulation, inflammation, signaling, hemostasis, reproduction, and [...] Read more.
Prostaglandins (PGs) are lipid mediators belonging to the eicosanoid family. PGs were first discovered in mammals where they are key players in a great variety of physiological and pathological processes, for instance muscle and blood vessel tone regulation, inflammation, signaling, hemostasis, reproduction, and sleep-wake regulation. These molecules have successively been discovered in lower organisms, including marine invertebrates in which they play similar roles to those in mammals, being involved in the control of oogenesis and spermatogenesis, ion transport, and defense. Prostaglandins have also been found in some marine macroalgae of the genera Gracilaria and Laminaria and very recently the PGs pathway has been identified for the first time in some species of marine microalgae. In this review we report on the occurrence of prostaglandins in the marine environment and discuss the anti-inflammatory role of these molecules. Full article
(This article belongs to the Special Issue Marine Anti-inflammatory Agents)
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