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Keywords = phaindole

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Article
Chemical Constituents of Phaius mishmensis
by Chen-Wei Jao, Tzu-Heng Hung, Chi-Fen Chang and Ta-Hsien Chuang
Molecules 2016, 21(11), 1605; https://doi.org/10.3390/molecules21111605 - 23 Nov 2016
Cited by 23 | Viewed by 5218
Abstract
The partitioned n-hexane, CHCl3, and EtOAc extracts from the crude MeOH extract of Phaius mishmensis showed considerable cytotoxicities against the human breast carcinoma (MCF-7), lung carcinoma (NCI-H460), and central nervous system carcinoma (SF-268) cell lines. Four new compounds, phaindole ( [...] Read more.
The partitioned n-hexane, CHCl3, and EtOAc extracts from the crude MeOH extract of Phaius mishmensis showed considerable cytotoxicities against the human breast carcinoma (MCF-7), lung carcinoma (NCI-H460), and central nervous system carcinoma (SF-268) cell lines. Four new compounds, phaindole (1), (7′R,8′R)-phaithrene (2), methyl 3-hydroxy-4,5-dimethoxypropiophenone (3), and methyl hematinate (4), as well as 44 known compounds were isolated from the MeOH extract of Phaius mishmensis. The structures of the compounds were determined using spectroscopic methods. Full article
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